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Page 1
Capturing the Dynamic Conformational Changes of Human Isocitrate Dehydrogenase 1 (IDH1) upon Ligand and Metal Binding Using Hydrogen-Deuterium Exchange Mass Spectrometry.
Sabo KA, Albekioni E, Caliger D, Coleman NJ, Thornberg E, Avellaneda Matteo D, Komives EA, Silletti S, Sohl CD. Sabo KA, et al. Among authors: silletti s. Biochemistry. 2023 Mar 21;62(6):1145-1159. doi: 10.1021/acs.biochem.2c00636. Epub 2023 Feb 28. Biochemistry. 2023. PMID: 36854124 Free PMC article.
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD. Mealka M, et al. Among authors: silletti s. bioRxiv [Preprint]. 2024 Jan 23:2024.01.10.574970. doi: 10.1101/2024.01.10.574970. bioRxiv. 2024. PMID: 38260668 Free PMC article. Preprint.
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD. Mealka M, et al. Among authors: silletti s. Res Sq [Preprint]. 2024 Feb 23:rs.3.rs-3889456. doi: 10.21203/rs.3.rs-3889456/v1. Res Sq. 2024. PMID: 38464189 Free PMC article. Preprint.
18 results