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Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound.
Kratz F, Warnecke A, Scheuermann K, Stockmar C, Schwab J, Lazar P, Drückes P, Esser N, Drevs J, Rognan D, Bissantz C, Hinderling C, Folkers G, Fichtner I, Unger C. Kratz F, et al. Among authors: stockmar c. J Med Chem. 2002 Dec 5;45(25):5523-33. doi: 10.1021/jm020276c. J Med Chem. 2002. PMID: 12459020
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