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Year Number of Results
1999 1
2001 1
2002 1
2003 2
2004 4
2005 5
2006 1
2007 1
2008 2
2009 3
2010 1
2011 1
2014 1
2015 1
2016 3
2017 1
2019 2
2020 2
2021 4
2022 3
2023 2
2024 2

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41 results

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Page 1
Tumor inflammation-associated neurotoxicity.
Mahdi J, Dietrich J, Straathof K, Roddie C, Scott BJ, Davidson TB, Prolo LM, Batchelor TT, Campen CJ, Davis KL, Gust J, Lim M, Majzner RG, Park JR, Partap S, Ramakrishna S, Richards R, Schultz L, Vitanza NA, Wang LD, Mackall CL, Monje M. Mahdi J, et al. Among authors: straathof k. Nat Med. 2023 Apr;29(4):803-810. doi: 10.1038/s41591-023-02276-w. Epub 2023 Apr 6. Nat Med. 2023. PMID: 37024595 Free PMC article. Review.
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.
Kildisiute G, Kholosy WM, Young MD, Roberts K, Elmentaite R, van Hooff SR, Pacyna CN, Khabirova E, Piapi A, Thevanesan C, Bugallo-Blanco E, Burke C, Mamanova L, Keller KM, Langenberg-Ververgaert KPS, Lijnzaad P, Margaritis T, Holstege FCP, Tas ML, Wijnen MHWA, van Noesel MM, Del Valle I, Barone G, van der Linden R, Duncan C, Anderson J, Achermann JC, Haniffa M, Teichmann SA, Rampling D, Sebire NJ, He X, de Krijger RR, Barker RA, Meyer KB, Bayraktar O, Straathof K, Molenaar JJ, Behjati S. Kildisiute G, et al. Among authors: straathof k. Sci Adv. 2021 Feb 5;7(6):eabd3311. doi: 10.1126/sciadv.abd3311. Print 2021 Feb. Sci Adv. 2021. PMID: 33547074 Free PMC article.
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.
Agliardi G, Liuzzi AR, Hotblack A, De Feo D, Núñez N, Stowe CL, Friebel E, Nannini F, Rindlisbacher L, Roberts TA, Ramasawmy R, Williams IP, Siow BM, Lythgoe MF, Kalber TL, Quezada SA, Pule MA, Tugues S, Straathof K, Becher B. Agliardi G, et al. Among authors: straathof k. Nat Commun. 2021 Jan 19;12(1):444. doi: 10.1038/s41467-020-20599-x. Nat Commun. 2021. PMID: 33469002 Free PMC article.
Antitumor activity without on-target off-tumor toxicity of GD2-chimeric antigen receptor T cells in patients with neuroblastoma.
Straathof K, Flutter B, Wallace R, Jain N, Loka T, Depani S, Wright G, Thomas S, Cheung GW, Gileadi T, Stafford S, Kokalaki E, Barton J, Marriott C, Rampling D, Ogunbiyi O, Akarca AU, Marafioti T, Inglott S, Gilmour K, Al-Hajj M, Day W, McHugh K, Biassoni L, Sizer N, Barton C, Edwards D, Dragoni I, Silvester J, Dyer K, Traub S, Elson L, Brook S, Westwood N, Robson L, Bedi A, Howe K, Barry A, Duncan C, Barone G, Pule M, Anderson J. Straathof K, et al. Sci Transl Med. 2020 Nov 25;12(571):eabd6169. doi: 10.1126/scitranslmed.abd6169. Sci Transl Med. 2020. PMID: 33239386
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Wienke J, Visser LL, Kholosy WM, Keller KM, Barisa M, Poon E, Munnings-Tomes S, Himsworth C, Calton E, Rodriguez A, Bernardi R, van den Ham F, van Hooff SR, Matser YAH, Tas ML, Langenberg KPS, Lijnzaad P, Borst AL, Zappa E, Bergsma FJ, Strijker JGM, Verhoeven BM, Mei S, Kramdi A, Restuadi R, Sanchez-Bernabeu A, Cornel AM, Holstege FCP, Gray JC, Tytgat GAM, Scheijde-Vermeulen MA, Wijnen MHWA, Dierselhuis MP, Straathof K, Behjati S, Wu W, Heck AJR, Koster J, Nierkens S, Janoueix-Lerosey I, de Krijger RR, Baryawno N, Chesler L, Anderson J, Caron HN, Margaritis T, van Noesel MM, Molenaar JJ. Wienke J, et al. Among authors: straathof k. Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4. Cancer Cell. 2024. PMID: 38181797 Free PMC article.
Inducible apoptosis as a safety switch for adoptive cell therapy.
Di Stasi A, Tey SK, Dotti G, Fujita Y, Kennedy-Nasser A, Martinez C, Straathof K, Liu E, Durett AG, Grilley B, Liu H, Cruz CR, Savoldo B, Gee AP, Schindler J, Krance RA, Heslop HE, Spencer DM, Rooney CM, Brenner MK. Di Stasi A, et al. Among authors: straathof k. N Engl J Med. 2011 Nov 3;365(18):1673-83. doi: 10.1056/NEJMoa1106152. N Engl J Med. 2011. PMID: 22047558 Free PMC article. Clinical Trial.
T cell therapies.
Gottschalk S, Bollard CM, Straathof KC, Louis CU, Savoldo B, Dotti G, Brenner MK, Heslop HE, Rooney CM. Gottschalk S, et al. Among authors: straathof kc. Ernst Schering Found Symp Proc. 2006;(4):69-82. doi: 10.1007/2789_2007_039. Ernst Schering Found Symp Proc. 2006. PMID: 17824182 Review.
Fine-tuning CARs for best performance.
Hotblack A, Straathof K. Hotblack A, et al. Among authors: straathof k. Cancer Cell. 2022 Jan 10;40(1):11-13. doi: 10.1016/j.ccell.2021.12.010. Cancer Cell. 2022. PMID: 35016025 Free article.
Embryonal precursors of Wilms tumor.
Coorens THH, Treger TD, Al-Saadi R, Moore L, Tran MGB, Mitchell TJ, Tugnait S, Thevanesan C, Young MD, Oliver TRW, Oostveen M, Collord G, Tarpey PS, Cagan A, Hooks Y, Brougham M, Reynolds BC, Barone G, Anderson J, Jorgensen M, Burke GAA, Visser J, Nicholson JC, Smeulders N, Mushtaq I, Stewart GD, Campbell PJ, Wedge DC, Martincorena I, Rampling D, Hook L, Warren AY, Coleman N, Chowdhury T, Sebire N, Drost J, Saeb-Parsy K, Stratton MR, Straathof K, Pritchard-Jones K, Behjati S. Coorens THH, et al. Among authors: straathof k. Science. 2019 Dec 6;366(6470):1247-1251. doi: 10.1126/science.aax1323. Science. 2019. PMID: 31806814 Free PMC article.
Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.
Khabirova E, Jardine L, Coorens THH, Webb S, Treger TD, Engelbert J, Porter T, Prigmore E, Collord G, Piapi A, Teichmann SA, Inglott S, Williams O, Heidenreich O, Young MD, Straathof K, Bomken S, Bartram J, Haniffa M, Behjati S. Khabirova E, et al. Among authors: straathof k. Nat Med. 2022 Apr;28(4):743-751. doi: 10.1038/s41591-022-01720-7. Epub 2022 Mar 14. Nat Med. 2022. PMID: 35288693 Free PMC article.
41 results