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The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
Vaughan RM, Kupai A, Foley CA, Sagum CA, Tibben BM, Eden HE, Tiedemann RL, Berryhill CA, Patel V, Shaw KM, Krajewski K, Strahl BD, Bedford MT, Frye SV, Dickson BM, Rothbart SB. Vaughan RM, et al. Among authors: strahl bd. Epigenetics Chromatin. 2020 Oct 23;13(1):44. doi: 10.1186/s13072-020-00366-4. Epigenetics Chromatin. 2020. PMID: 33097091 Free PMC article.
CCR4/NOT complex associates with the proteasome and regulates histone methylation.
Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. Laribee RN, et al. Among authors: strahl bd. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5836-41. doi: 10.1073/pnas.0607996104. Epub 2007 Mar 26. Proc Natl Acad Sci U S A. 2007. PMID: 17389396 Free PMC article.
Peptide microarrays to interrogate the "histone code".
Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Rothbart SB, et al. Among authors: strahl bd. Methods Enzymol. 2012;512:107-35. doi: 10.1016/B978-0-12-391940-3.00006-8. Methods Enzymol. 2012. PMID: 22910205 Free PMC article.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Rothbart SB, et al. Among authors: strahl bd. Nat Struct Mol Biol. 2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30. Nat Struct Mol Biol. 2012. PMID: 23022729 Free PMC article.
186 results