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WAY-318068: a novel, potent and selective noradrenaline re-uptake inhibitor with activity in rodent models of pain and depression.
Whiteside GT, Dwyer JM, Harrison JE, Beyer CE, Cummons T, Manzino L, Mark L, Johnston GH, Strassle BW, Adedoyin A, Lu P, Piesla MJ, Pulicicchio CM, Erve JC, Platt BJ, Hughes ZA, Rogers KE, Deecher DC, Trybulski EJ, Kennedy JD, Zhang P, Leventhal L. Whiteside GT, et al. Among authors: strassle bw. Br J Pharmacol. 2010 Jul;160(5):1105-18. doi: 10.1111/j.1476-5381.2010.00690.x. Br J Pharmacol. 2010. PMID: 20590604 Free PMC article.
Species-specific in vitro pharmacological effects of the cannabinoid receptor 2 (CB2) selective ligand AM1241 and its resolved enantiomers.
Bingham B, Jones PG, Uveges AJ, Kotnis S, Lu P, Smith VA, Sun SC, Resnick L, Chlenov M, He Y, Strassle BW, Cummons TA, Piesla MJ, Harrison JE, Whiteside GT, Kennedy JD. Bingham B, et al. Among authors: strassle bw. Br J Pharmacol. 2007 Aug;151(7):1061-70. doi: 10.1038/sj.bjp.0707303. Epub 2007 Jun 4. Br J Pharmacol. 2007. PMID: 17549048 Free PMC article.
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system.
Chanda PK, Gao Y, Mark L, Btesh J, Strassle BW, Lu P, Piesla MJ, Zhang MY, Bingham B, Uveges A, Kowal D, Garbe D, Kouranova EV, Ring RH, Bates B, Pangalos MN, Kennedy JD, Whiteside GT, Samad TA. Chanda PK, et al. Among authors: strassle bw. Mol Pharmacol. 2010 Dec;78(6):996-1003. doi: 10.1124/mol.110.068304. Epub 2010 Sep 20. Mol Pharmacol. 2010. PMID: 20855465
Pharmacological characterization of the muscarinic agonist (3R,4R)-3-(3-hexylsulfanyl-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane (WAY-132983) in in vitro and in vivo models of chronic pain.
Sullivan NR, Leventhal L, Harrison J, Smith VA, Cummons TA, Spangler TB, Sun SC, Lu P, Uveges AJ, Strassle BW, Piesla MJ, Ramdass R, Barry A, Schantz J, Adams W, Whiteside GT, Adedoyin A, Jones PG. Sullivan NR, et al. Among authors: strassle bw. J Pharmacol Exp Ther. 2007 Sep;322(3):1294-304. doi: 10.1124/jpet.106.118604. Epub 2007 Jun 22. J Pharmacol Exp Ther. 2007. PMID: 17586724
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.
Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, Shen R, Zhang MY, Strassle BW, Lu P, Mark L, Piesla MJ, Deng K, Kouranova EV, Ring RH, Whiteside GT, Bates B, Walsh FS, Williams G, Pangalos MN, Samad TA, Doherty P. Gao Y, et al. Among authors: strassle bw. J Neurosci. 2010 Feb 10;30(6):2017-24. doi: 10.1523/JNEUROSCI.5693-09.2010. J Neurosci. 2010. PMID: 20147530 Free PMC article.
A model of cystitis pain in the mouse.
Leventhal L, Strassle B. Leventhal L, et al. Curr Protoc Pharmacol. 2008 Dec;Chapter 5:Unit 5.52. doi: 10.1002/0471141755.ph0552s43. Curr Protoc Pharmacol. 2008. PMID: 22294232
Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain.
von Schack D, Agostino MJ, Murray BS, Li Y, Reddy PS, Chen J, Choe SE, Strassle BW, Li C, Bates B, Zhang L, Hu H, Kotnis S, Bingham B, Liu W, Whiteside GT, Samad TA, Kennedy JD, Ajit SK. von Schack D, et al. Among authors: strassle bw. PLoS One. 2011 Mar 14;6(3):e17670. doi: 10.1371/journal.pone.0017670. PLoS One. 2011. PMID: 21423802 Free PMC article.
19 results