Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin.
Gendron L, Esdaile MJ, Mennicken F, Pan H, O'Donnell D, Vincent JP, Devi LA, Cahill CM, Stroh T, Beaudet A.
Gendron L, et al. Among authors: stroh t.
Neuroscience. 2007 Jan 5;144(1):263-74. doi: 10.1016/j.neuroscience.2006.08.077. Epub 2006 Oct 19.
Neuroscience. 2007.
PMID: 17055663
We found that chronic inflammation produced by injection of complete Freund's adjuvant (CFA) into the hind paw resulted in a bilateral increase in the binding and internalization of fluorescent deltorphin in neurons of the lumbar spinal cord as did prolonged morphine treatment [M …
We found that chronic inflammation produced by injection of complete Freund's adjuvant (CFA) into the hind paw resulted in a bilateral incre …