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Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.
Correia BE, Ban YE, Holmes MA, Xu H, Ellingson K, Kraft Z, Carrico C, Boni E, Sather DN, Zenobia C, Burke KY, Bradley-Hewitt T, Bruhn-Johannsen JF, Kalyuzhniy O, Baker D, Strong RK, Stamatatos L, Schief WR. Correia BE, et al. Among authors: strong rk. Structure. 2010 Sep 8;18(9):1116-26. doi: 10.1016/j.str.2010.06.010. Structure. 2010. PMID: 20826338 Free article.
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.
McGuire AT, Gray MD, Dosenovic P, Gitlin AD, Freund NT, Petersen J, Correnti C, Johnsen W, Kegel R, Stuart AB, Glenn J, Seaman MS, Schief WR, Strong RK, Nussenzweig MC, Stamatatos L. McGuire AT, et al. Among authors: strong rk. Nat Commun. 2016 Feb 24;7:10618. doi: 10.1038/ncomms10618. Nat Commun. 2016. PMID: 26907590 Free PMC article.
Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
Bancroft T, DeBuysscher BL, Weidle C, Schwartz A, Wall A, Gray MD, Feng J, Steach HR, Fitzpatrick KS, Gewe MM, Skog PD, Doyle-Cooper C, Ota T, Strong RK, Nemazee D, Pancera M, Stamatatos L, McGuire AT, Taylor JJ. Bancroft T, et al. Among authors: strong rk. J Exp Med. 2019 Oct 7;216(10):2331-2347. doi: 10.1084/jem.20190164. Epub 2019 Jul 25. J Exp Med. 2019. PMID: 31345930 Free PMC article. Clinical Trial.
Evaluation of Cell-Based and Surrogate SARS-CoV-2 Neutralization Assays.
Sholukh AM, Fiore-Gartland A, Ford ES, Miner MD, Hou YJ, Tse LV, Kaiser H, Zhu H, Lu J, Madarampalli B, Park A, Lempp FA, St Germain R, Bossard EL, Kee JJ, Diem K, Stuart AB, Rupert PB, Brock C, Buerger M, Doll MK, Randhawa AK, Stamatatos L, Strong RK, McLaughlin C, Huang ML, Jerome KR, Baric RS, Montefiori D, Corey L. Sholukh AM, et al. Among authors: strong rk. J Clin Microbiol. 2021 Sep 20;59(10):e0052721. doi: 10.1128/JCM.00527-21. Epub 2021 Jul 21. J Clin Microbiol. 2021. PMID: 34288726 Free PMC article.
121 results