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Page 1
Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.
Farge T, Saland E, de Toni F, Aroua N, Hosseini M, Perry R, Bosc C, Sugita M, Stuani L, Fraisse M, Scotland S, Larrue C, Boutzen H, Féliu V, Nicolau-Travers ML, Cassant-Sourdy S, Broin N, David M, Serhan N, Sarry A, Tavitian S, Kaoma T, Vallar L, Iacovoni J, Linares LK, Montersino C, Castellano R, Griessinger E, Collette Y, Duchamp O, Barreira Y, Hirsch P, Palama T, Gales L, Delhommeau F, Garmy-Susini BH, Portais JC, Vergez F, Selak M, Danet-Desnoyers G, Carroll M, Récher C, Sarry JE. Farge T, et al. Among authors: cassant sourdy s. Cancer Discov. 2017 Jul;7(7):716-735. doi: 10.1158/2159-8290.CD-16-0441. Epub 2017 Apr 17. Cancer Discov. 2017. PMID: 28416471 Free PMC article.
ChREBPβ is dispensable for the control of glucose homeostasis and energy balance.
Recazens E, Tavernier G, Dufau J, Bergoglio C, Benhamed F, Cassant-Sourdy S, Marques MA, Caspar-Bauguil S, Brion A, Monbrun L, Dentin R, Ferrier C, Leroux M, Denechaud PD, Moro C, Concordet JP, Postic C, Mouisel E, Langin D. Recazens E, et al. Among authors: cassant sourdy s. JCI Insight. 2022 Feb 22;7(4):e153431. doi: 10.1172/jci.insight.153431. JCI Insight. 2022. PMID: 35041621 Free PMC article.
Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component.
Thibault B, Ramos-Delgado F, Pons-Tostivint E, Therville N, Cintas C, Arcucci S, Cassant-Sourdy S, Reyes-Castellanos G, Tosolini M, Villard AV, Cayron C, Baer R, Bertrand-Michel J, Pagan D, Ferreira Da Mota D, Yan H, Falcomatà C, Muscari F, Bournet B, Delord JP, Aksoy E, Carrier A, Cordelier P, Saur D, Basset C, Guillermet-Guibert J. Thibault B, et al. Among authors: cassant sourdy s. EMBO Mol Med. 2021 Jul 7;13(7):e13502. doi: 10.15252/emmm.202013502. Epub 2021 May 25. EMBO Mol Med. 2021. PMID: 34033220 Free PMC article.
Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages.
Samain R, Brunel A, Douché T, Fanjul M, Cassant-Sourdy S, Rochotte J, Cros J, Neuzillet C, Raffenne J, Duluc C, Perraud A, Nigri J, Gigoux V, Bieche I, Ponzo M, Carpentier G, Cascone I, Tomasini R, Schmid HA, Mathonnet M, Nicolle R, Bousquet MP, Martineau Y, Pyronnet S, Jean C, Bousquet C. Samain R, et al. Among authors: cassant sourdy s. Cell Mol Gastroenterol Hepatol. 2021;11(5):1405-1436. doi: 10.1016/j.jcmgh.2021.01.008. Epub 2021 Jan 20. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33482394 Free PMC article.
Nucleolin Promotes Heat Shock-Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis.
Morfoisse F, Tatin F, Hantelys F, Adoue A, Helfer AC, Cassant-Sourdy S, Pujol F, Gomez-Brouchet A, Ligat L, Lopez F, Pyronnet S, Courty J, Guillermet-Guibert J, Marzi S, Schneider RJ, Prats AC, Garmy-Susini BH. Morfoisse F, et al. Among authors: cassant sourdy s. Cancer Res. 2016 Aug 1;76(15):4394-405. doi: 10.1158/0008-5472.CAN-15-3140. Epub 2016 Jun 8. Cancer Res. 2016. PMID: 27280395 Free article.
FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant-Sourdy S, Rochotte J, Brunel A, Schlaepfer D, Cros J, Neuzillet C, Strehaiano M, Alard A, Tomasini R, Rajeeve V, Perraud A, Mathonnet M, Pearce OM, Martineau Y, Pyronnet S, Bousquet C, Jean C. Zaghdoudi S, et al. Among authors: cassant sourdy s. EMBO Mol Med. 2020 Nov 6;12(11):e12010. doi: 10.15252/emmm.202012010. Epub 2020 Oct 7. EMBO Mol Med. 2020. PMID: 33025708 Free PMC article.
Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts.
Moatassim-Billah S, Duluc C, Samain R, Jean C, Perraud A, Decaup E, Cassant-Sourdy S, Bakri Y, Selves J, Schmid H, Martineau Y, Mathonnet M, Pyronnet S, Bousquet C. Moatassim-Billah S, et al. Among authors: cassant sourdy s. Oncotarget. 2016 Jul 5;7(27):41584-41598. doi: 10.18632/oncotarget.9296. Oncotarget. 2016. PMID: 27177087 Free PMC article.
Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
Baer R, Cintas C, Dufresne M, Cassant-Sourdy S, Schönhuber N, Planque L, Lulka H, Couderc B, Bousquet C, Garmy-Susini B, Vanhaesebroeck B, Pyronnet S, Saur D, Guillermet-Guibert J. Baer R, et al. Among authors: cassant sourdy s. Genes Dev. 2014 Dec 1;28(23):2621-35. doi: 10.1101/gad.249409.114. Genes Dev. 2014. PMID: 25452273 Free PMC article.
Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C. Chalabi-Dchar M, et al. Among authors: cassant sourdy s. Gastroenterology. 2015 Jun;148(7):1452-65. doi: 10.1053/j.gastro.2015.02.009. Epub 2015 Feb 13. Gastroenterology. 2015. PMID: 25683115