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L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.
Shim EH, Livi CB, Rakheja D, Tan J, Benson D, Parekh V, Kho EY, Ghosh AP, Kirkman R, Velu S, Dutta S, Chenna B, Rea SL, Mishur RJ, Li Q, Johnson-Pais TL, Guo L, Bae S, Wei S, Block K, Sudarshan S. Shim EH, et al. Among authors: sudarshan s. Cancer Discov. 2014 Nov;4(11):1290-8. doi: 10.1158/2159-8290.CD-13-0696. Epub 2014 Sep 2. Cancer Discov. 2014. PMID: 25182153 Free PMC article.
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Shelar S, Shim EH, Brinkley GJ, Kundu A, Carobbio F, Poston T, Tan J, Parekh V, Benson D, Crossman DK, Buckhaults PJ, Rakheja D, Kirkman R, Sato Y, Ogawa S, Dutta S, Velu SE, Emberley E, Pan A, Chen J, Huang T, Absher D, Becker A, Kunick C, Sudarshan S. Shelar S, et al. Among authors: sudarshan s. Clin Cancer Res. 2018 Dec 15;24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727. Epub 2018 Aug 14. Clin Cancer Res. 2018. PMID: 30108105 Free PMC article.
Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.
Brinkley G, Nam H, Shim E, Kirkman R, Kundu A, Karki S, Heidarian Y, Tennessen JM, Liu J, Locasale JW, Guo T, Wei S, Gordetsky J, Johnson-Pais TL, Absher D, Rakheja D, Challa AK, Sudarshan S. Brinkley G, et al. Among authors: sudarshan s. Dis Model Mech. 2020 Nov 27;13(11):dmm045898. doi: 10.1242/dmm.045898. Dis Model Mech. 2020. PMID: 32928875 Free PMC article.
The oncometabolite L-2-hydroxyglutarate is a common product of dipteran larval development.
Mahmoudzadeh NH, Fitt AJ, Schwab DB, Martenis WE, Nease LM, Owings CG, Brinkley GJ, Li H, Karty JA, Sudarshan S, Hardy RW, Moczek AP, Picard CJ, Tennessen JM. Mahmoudzadeh NH, et al. Among authors: sudarshan s. Insect Biochem Mol Biol. 2020 Dec;127:103493. doi: 10.1016/j.ibmb.2020.103493. Epub 2020 Nov 3. Insect Biochem Mol Biol. 2020. PMID: 33157229 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34005075
Genetics of renal cancer: focus on MTOR.
Ghosh AP, Sudarshan S. Ghosh AP, et al. Among authors: sudarshan s. Aging (Albany NY). 2016 Mar;8(3):421-2. doi: 10.18632/aging.100937. Aging (Albany NY). 2016. PMID: 27017990 Free PMC article. No abstract available.
PRDM16 suppresses HIF-targeted gene expression in kidney cancer.
Kundu A, Nam H, Shelar S, Chandrashekar DS, Brinkley G, Karki S, Mitchell T, Livi CB, Buckhaults P, Kirkman R, Tang Y, Rowe GC, Wei S, Varambally S, Sudarshan S. Kundu A, et al. Among authors: sudarshan s. J Exp Med. 2020 Jun 1;217(6):e20191005. doi: 10.1084/jem.20191005. J Exp Med. 2020. PMID: 32251515 Free PMC article.
115 results