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Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.
LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK. LaFargue CJ, et al. Among authors: umamaheswaran s. Nat Commun. 2023 Apr 26;14(1):2407. doi: 10.1038/s41467-023-36910-5. Nat Commun. 2023. PMID: 37100807 Free PMC article.
Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Wen Y, Chelariu-Raicu A, Umamaheswaran S, Nick AM, Stur E, Hanjra P, Jiang D, Jennings NB, Chen X, Corvigno S, Glassman D, Lopez-Berestein G, Liu J, Hung MC, Sood AK. Wen Y, et al. Among authors: umamaheswaran s. Cell Rep. 2023 Mar 28;42(3):112154. doi: 10.1016/j.celrep.2023.112154. Cell Rep. 2023. PMID: 37274180 Free PMC article. No abstract available.
Stress, inflammation, and eicosanoids: an emerging perspective.
Umamaheswaran S, Dasari SK, Yang P, Lutgendorf SK, Sood AK. Umamaheswaran S, et al. Cancer Metastasis Rev. 2018 Sep;37(2-3):203-211. doi: 10.1007/s10555-018-9741-1. Cancer Metastasis Rev. 2018. PMID: 29948328 Free PMC article. Review.
EphA2- and HDAC-Targeted Combination Therapy in Endometrial Cancer.
Joseph R, Dasari SK, Umamaheswaran S, Mangala LS, Bayraktar E, Rodriguez-Aguayo C, Wu Y, Nguyen N, Powell RT, Sobieski M, Liu Y, Kim MS, Corvigno S, Foster K, Hanjra P, Vu TC, Chowdhury MA, Amero P, Stephan C, Lopez-Berestein G, Westin SN, Sood AK. Joseph R, et al. Among authors: umamaheswaran s. Int J Mol Sci. 2024 Jan 20;25(2):1278. doi: 10.3390/ijms25021278. Int J Mol Sci. 2024. PMID: 38279277 Free PMC article.
Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Wen Y, Chelariu-Raicu A, Umamaheswaran S, Nick AM, Stur E, Hanjra P, Jiang D, Jennings NB, Chen X, Corvigno S, Glassman D, Lopez-Berestein G, Liu J, Hung MC, Sood AK. Wen Y, et al. Among authors: umamaheswaran s. Cell Rep. 2022 Jan 25;38(4):110301. doi: 10.1016/j.celrep.2022.110301. Cell Rep. 2022. PMID: 35081345 Free PMC article.
Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Wen Y, Chelariu-Raicu A, Umamaheswaran S, Nick AM, Stur E, Hanjra P, Jiang D, Jennings NB, Chen X, Corvigno S, Glassman D, Lopez-Berestein G, Liu J, Hung MC, Sood AK. Wen Y, et al. Among authors: umamaheswaran s. Cell Rep. 2022 Jun 21;39(12):110999. doi: 10.1016/j.celrep.2022.110999. Cell Rep. 2022. PMID: 35732127 Free PMC article. No abstract available.
Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer.
Dasari SK, Joseph R, Umamaheswaran S, Mangala LS, Bayraktar E, Rodriguez-Aguayo C, Wu Y, Nguyen N, Powell RT, Sobieski M, Liu Y, Chowdhury MA, Amero P, Stephan C, Lopez-Berestein G, Westin SN, Sood AK. Dasari SK, et al. Among authors: umamaheswaran s. Int J Mol Sci. 2023 Feb 15;24(4):3915. doi: 10.3390/ijms24043915. Int J Mol Sci. 2023. PMID: 36835335 Free PMC article.
TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.
Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z. Berrout J, et al. Among authors: umamaheswaran s. Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w. Nat Commun. 2017. PMID: 29038531 Free PMC article.
Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models.
Handley KF, Rodriguez-Aguayo C, Ma S, Stur E, Joseph R, Bayraktar E, Dasari SK, Nguyen N, Powell RT, Sobieski M, Ivan C, Kim M, Umamaheswaran S, Glassman D, Wen Y, Amero P, Stephan C, Coleman RL, Landesman Y, Westin SN, Ram PT, Sood AK. Handley KF, et al. Among authors: umamaheswaran s. Mol Cancer Ther. 2021 Dec;20(12):2352-2361. doi: 10.1158/1535-7163.MCT-21-0370. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583979 Free PMC article.