Sukhatme VP - Search Results

1

The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.

Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH. Hanai J, et al. Among authors: sukhatme vp. J Clin Invest. 2007 Dec;117(12):3940-51. doi: 10.1172/JCI32741. J Clin Invest. 2007. PMID: 17992259 Free PMC article.

2

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.

Cao P, Hanai J, Tanksale P, Imamura S, Sukhatme VP, Lecker SH. Cao P, et al. Among authors: sukhatme vp. FASEB J. 2009 Sep;23(9):2844-54. doi: 10.1096/fj.08-128843. Epub 2009 Apr 30. FASEB J. 2009. PMID: 19406843 Free PMC article.

3

Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways.

Hanai J, Doro N, Sasaki AT, Kobayashi S, Cantley LC, Seth P, Sukhatme VP. Hanai J, et al. Among authors: sukhatme vp. J Cell Physiol. 2012 Apr;227(4):1709-20. doi: 10.1002/jcp.22895. J Cell Physiol. 2012. PMID: 21688263 Free PMC article.

4

A small-molecule screening strategy to identify suppressors of statin myopathy.

Wagner BK, Gilbert TJ, Hanai J, Imamura S, Bodycombe NE, Bon RS, Waldmann H, Clemons PA, Sukhatme VP, Mootha VK. Wagner BK, et al. Among authors: sukhatme vp. ACS Chem Biol. 2011 Sep 16;6(9):900-4. doi: 10.1021/cb200206w. Epub 2011 Jul 15. ACS Chem Biol. 2011. PMID: 21732624 Free PMC article.

5

Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3.

Feinberg MW, Watanabe M, Lebedeva MA, Depina AS, Hanai J, Mammoto T, Frederick JP, Wang XF, Sukhatme VP, Jain MK. Feinberg MW, et al. Among authors: sukhatme vp. J Biol Chem. 2004 Apr 16;279(16):16388-93. doi: 10.1074/jbc.M309664200. Epub 2004 Feb 1. J Biol Chem. 2004. PMID: 14754879 Free article.

6

A critical role for calponin 2 in vascular development.

Tang J, Hu G, Hanai J, Yadlapalli G, Lin Y, Zhang B, Galloway J, Bahary N, Sinha S, Thisse B, Thisse C, Jin JP, Zon LI, Sukhatme VP. Tang J, et al. Among authors: sukhatme vp. J Biol Chem. 2006 Mar 10;281(10):6664-72. doi: 10.1074/jbc.M506991200. Epub 2005 Nov 28. J Biol Chem. 2006. PMID: 16317011 Free article.

7

A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro.

Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP. Hu G, et al. Among authors: sukhatme vp. J Cell Sci. 2006 Oct 1;119(Pt 19):4117-26. doi: 10.1242/jcs.03179. Epub 2006 Sep 12. J Cell Sci. 2006. PMID: 16968741

8

Lipocalin 2 antagonizes the proangiogenic action of ras in transformed cells.

Venkatesha S, Hanai J, Seth P, Karumanchi SA, Sukhatme VP. Venkatesha S, et al. Among authors: sukhatme vp. Mol Cancer Res. 2006 Nov;4(11):821-9. doi: 10.1158/1541-7786.MCR-06-0110. Mol Cancer Res. 2006. PMID: 17114340

9

Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.

Jernigan FE, Hanai JI, Sukhatme VP, Sun L. Jernigan FE, et al. Among authors: sukhatme vp. Bioorg Med Chem Lett. 2017 Feb 15;27(4):929-935. doi: 10.1016/j.bmcl.2017.01.001. Epub 2017 Jan 16. Bioorg Med Chem Lett. 2017. PMID: 28129980

10

Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.

Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP. Hanai J, et al. Among authors: sukhatme vp. J Biol Chem. 2002 May 10;277(19):16464-9. doi: 10.1074/jbc.M112274200. Epub 2002 Jan 28. J Biol Chem. 2002. PMID: 11815623 Free article.

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