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A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile.
Sacco MD, Wang S, Adapa SR, Zhang X, Lewandowski EM, Gongora MV, Keramisanou D, Atlas ZD, Townsend JA, Gatdula JR, Morgan RT, Hammond LR, Marty MT, Wang J, Eswara PJ, Gelis I, Jiang RHY, Sun X, Chen Y. Sacco MD, et al. Among authors: sun x. Nat Commun. 2022 Jul 28;13(1):4370. doi: 10.1038/s41467-022-32086-6. Nat Commun. 2022. PMID: 35902581 Free PMC article.
Oral Immunization with Nontoxigenic Clostridium difficile Strains Expressing Chimeric Fragments of TcdA and TcdB Elicits Protective Immunity against C. difficile Infection in Both Mice and Hamsters.
Wang Y, Wang S, Bouillaut L, Li C, Duan Z, Zhang K, Ju X, Tzipori S, Sonenshein AL, Sun X. Wang Y, et al. Among authors: sun x. Infect Immun. 2018 Oct 25;86(11):e00489-18. doi: 10.1128/IAI.00489-18. Print 2018 Nov. Infect Immun. 2018. PMID: 30150259 Free PMC article.
Clostridioides difficile phage biology and application.
Heuler J, Fortier LC, Sun X. Heuler J, et al. Among authors: sun x. FEMS Microbiol Rev. 2021 Sep 8;45(5):fuab012. doi: 10.1093/femsre/fuab012. FEMS Microbiol Rev. 2021. PMID: 33580957 Free PMC article. Review.
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