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The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.
Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL. Boone MA, et al. Among authors: sunkel bd. Oncogene. 2021 Jul;40(29):4759-4769. doi: 10.1038/s41388-021-01876-5. Epub 2021 Jun 18. Oncogene. 2021. PMID: 34145397 Free PMC article.
SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation.
Wang L, Hensch NR, Bondra K, Sreenivas P, Zhao XR, Chen J, Moreno Campos R, Baxi K, Vaseva AV, Sunkel BD, Gryder BE, Pomella S, Stanton BZ, Zheng S, Chen EY, Rota R, Khan J, Houghton PJ, Ignatius MS. Wang L, et al. Among authors: sunkel bd. Cancer Res. 2021 Nov 1;81(21):5451-5463. doi: 10.1158/0008-5472.CAN-20-4191. Epub 2021 Aug 30. Cancer Res. 2021. PMID: 34462275 Free PMC article.
Pioneer factors in development and cancer.
Sunkel BD, Stanton BZ. Sunkel BD, et al. iScience. 2021 Sep 15;24(10):103132. doi: 10.1016/j.isci.2021.103132. eCollection 2021 Oct 22. iScience. 2021. PMID: 34632331 Free PMC article. Review.
BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma.
Laubscher D, Gryder BE, Sunkel BD, Andresson T, Wachtel M, Das S, Roschitzki B, Wolski W, Wu XS, Chou HC, Song YK, Wang C, Wei JS, Wang M, Wen X, Ngo QA, Marques JG, Vakoc CR, Schäfer BW, Stanton BZ, Khan J. Laubscher D, et al. Among authors: sunkel bd. Nat Commun. 2021 Nov 26;12(1):6924. doi: 10.1038/s41467-021-27176-w. Nat Commun. 2021. PMID: 34836971 Free PMC article.
Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation.
Chen X, Sunkel B, Wang M, Kang S, Wang T, Gnanaprakasam JNR, Liu L, Cassel TA, Scott DA, Muñoz-Cabello AM, Lopez-Barneo J, Yang J, Lane AN, Xin G, Stanton BZ, Fan TW, Wang R. Chen X, et al. Sci Immunol. 2022 Apr 29;7(70):eabm8161. doi: 10.1126/sciimmunol.abm8161. Epub 2022 Apr 29. Sci Immunol. 2022. PMID: 35486677 Free PMC article.
Chromatin structure in cancer.
Wang M, Sunkel BD, Ray WC, Stanton BZ. Wang M, et al. Among authors: sunkel bd. BMC Mol Cell Biol. 2022 Jul 28;23(1):35. doi: 10.1186/s12860-022-00433-6. BMC Mol Cell Biol. 2022. PMID: 35902807 Free PMC article. Review.
The 3D chromatin landscape of rhabdomyosarcoma.
Wang M, Sreenivas P, Sunkel BD, Wang L, Ignatius M, Stanton BZ. Wang M, et al. Among authors: sunkel bd. NAR Cancer. 2023 Jun 13;5(3):zcad028. doi: 10.1093/narcan/zcad028. eCollection 2023 Sep. NAR Cancer. 2023. PMID: 37325549 Free PMC article.
A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma.
Sreenivas P, Wang L, Wang M, Challa A, Modi P, Hensch NR, Gryder B, Chou HC, Zhao XR, Sunkel B, Moreno-Campos R, Khan J, Stanton BZ, Ignatius MS. Sreenivas P, et al. Mol Cell Biol. 2023;43(11):547-565. doi: 10.1080/10985549.2023.2256640. Epub 2023 Nov 17. Mol Cell Biol. 2023. PMID: 37882064 Free PMC article.
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