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The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders.
Li X, Kheirabadi M, Dougherty PG, Kamer KJ, Shen X, Estrella NL, Peddigari S, Pathak A, Blake SL, Sizensky E, Genio CD, Gaur AB, Dhanabal M, Girgenrath M, Sethuraman N, Qian Z. Li X, et al. Among authors: peddigari s. Mol Ther Nucleic Acids. 2023 Jun 29;33:273-285. doi: 10.1016/j.omtn.2023.06.022. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37538053 Free PMC article.
Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.
Domostegui A, Peddigari S, Mercer CA, Iannizzotto F, Rodriguez ML, Garcia-Cajide M, Amador V, Diepstraten ST, Kelly GL, Salazar R, Kozma SC, Kusnadi EP, Kang J, Gentilella A, Pearson RB, Thomas G, Pelletier J. Domostegui A, et al. Among authors: peddigari s. Blood. 2021 Jun 17;137(24):3351-3364. doi: 10.1182/blood.2020007452. Blood. 2021. PMID: 33512431 Free PMC article.