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EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer.
Clancy JL, Henderson MJ, Russell AJ, Anderson DW, Bova RJ, Campbell IG, Choong DY, Macdonald GA, Mann GJ, Nolan T, Brady G, Olopade OI, Woollatt E, Davies MJ, Segara D, Hacker NF, Henshall SM, Sutherland RL, Watts CK. Clancy JL, et al. Among authors: sutherland rl. Oncogene. 2003 Aug 7;22(32):5070-81. doi: 10.1038/sj.onc.1206775. Oncogene. 2003. PMID: 12902990
EDD mediates DNA damage-induced activation of CHK2.
Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK. Henderson MJ, et al. Among authors: sutherland rl. J Biol Chem. 2006 Dec 29;281(52):39990-40000. doi: 10.1074/jbc.M602818200. Epub 2006 Oct 30. J Biol Chem. 2006. PMID: 17074762 Free article.
Oestrogen receptor gene structure and function in breast cancer.
Watts CK, Handel ML, King RJ, Sutherland RL. Watts CK, et al. Among authors: sutherland rl. J Steroid Biochem Mol Biol. 1992 Mar;41(3-8):529-36. doi: 10.1016/0960-0760(92)90378-v. J Steroid Biochem Mol Biol. 1992. PMID: 1562523
390 results