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Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study.
Mav D, Phadke DP, Balik-Meisner MR, Merrick BA, Auerbach S, Niemeijer M, Huppelschoten S, Baze A, Parmentier C, Richert L, van de Water B, Shah RR, Paules RS. Mav D, et al. Among authors: huppelschoten s. Bioinform Biol Insights. 2020 Sep 29;14:1177932220952742. doi: 10.1177/1177932220952742. eCollection 2020. Bioinform Biol Insights. 2020. PMID: 33088175 Free PMC article.
The hepatotoxic fluoroquinolone trovafloxacin disturbs TNF- and LPS-induced p65 nuclear translocation in vivo and in vitro.
Giustarini G, Huppelschoten S, Barra M, Oppelt A, Wagenaar L, Weaver RJ, Bol-Schoenmakers M, Smit JJ, van de Water B, Klingmüller U, Pieters RHH. Giustarini G, et al. Among authors: huppelschoten s. Toxicol Appl Pharmacol. 2020 Mar 15;391:114915. doi: 10.1016/j.taap.2020.114915. Epub 2020 Feb 6. Toxicol Appl Pharmacol. 2020. PMID: 32035082
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors.
Niemeijer M, Więcek W, Fu S, Huppelschoten S, Bouwman P, Baze A, Parmentier C, Richert L, Paules RS, Bois FY, van de Water B. Niemeijer M, et al. Among authors: huppelschoten s. Environ Health Perspect. 2024 Mar;132(3):37005. doi: 10.1289/EHP11891. Epub 2024 Mar 18. Environ Health Perspect. 2024. PMID: 38498338 Free PMC article.
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.
Ter Braak B, Niemeijer M, Boon R, Parmentier C, Baze A, Richert L, Huppelschoten S, Wink S, Verfaillie C, van de Water B. Ter Braak B, et al. Among authors: huppelschoten s. Toxicol In Vitro. 2021 Jun;73:105107. doi: 10.1016/j.tiv.2021.105107. Epub 2021 Feb 3. Toxicol In Vitro. 2021. PMID: 33545341 Free article.
Vaccine-induced tumor necrosis factor-producing T cells synergize with cisplatin to promote tumor cell death.
van der Sluis TC, van Duikeren S, Huppelschoten S, Jordanova ES, Beyranvand Nejad E, Sloots A, Boon L, Smit VT, Welters MJ, Ossendorp F, van de Water B, Arens R, van der Burg SH, Melief CJ. van der Sluis TC, et al. Among authors: huppelschoten s. Clin Cancer Res. 2015 Feb 15;21(4):781-94. doi: 10.1158/1078-0432.CCR-14-2142. Epub 2014 Dec 12. Clin Cancer Res. 2015. PMID: 25501579
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U. Oppelt A, et al. Among authors: huppelschoten s. NPJ Syst Biol Appl. 2018 Jun 11;4:23. doi: 10.1038/s41540-018-0058-z. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29900006 Free PMC article.