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Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction.
ACS Chem Neurosci. 2013 Jan 16;4(1):110-21. doi: 10.1021/cn300072u. Epub 2012 Aug 11.
ACS Chem Neurosci. 2013.
PMID: 23336050
Free PMC article.
Variation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivity.
Anastasio NC, Liu S, Maili L, Swinford SE, Lane SD, Fox RG, Hamon SC, Nielsen DA, Cunningham KA, Moeller FG.
Anastasio NC, et al. Among authors: swinford se.
Transl Psychiatry. 2014 Mar 11;4(3):e369. doi: 10.1038/tp.2013.131.
Transl Psychiatry. 2014.
PMID: 24618688
Free PMC article.
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Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.
Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW Jr, Laezza FM, Watson CS, Briggs JM, Cunningham KA.
Anastasio NC, et al. Among authors: swinford se.
J Neurosci. 2013 Jan 23;33(4):1615-30. doi: 10.1523/JNEUROSCI.2656-12.2013.
J Neurosci. 2013.
PMID: 23345234
Free PMC article.
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Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats.
Pockros LA, Pentkowski NS, Swinford SE, Neisewander JL.
Pockros LA, et al. Among authors: swinford se.
Psychopharmacology (Berl). 2011 Feb;213(2-3):307-20. doi: 10.1007/s00213-010-2071-9. Epub 2010 Nov 16.
Psychopharmacology (Berl). 2011.
PMID: 21079923
Free PMC article.
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