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Year Number of Results
2007 1
2008 1
2009 2
2010 2
2012 1
2013 1
2014 4
2015 3
2016 2
2017 1
2018 1
2019 4
2020 3
2021 5
2022 1
2023 4
2024 2

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35 results

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Page 1
PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Seif-El-Dahan M, Kefala-Stavridi A, Frit P, Hardwick SW, Chirgadze DY, Maia De Oliviera T, Andreani J, Britton S, Barboule N, Bossaert M, Pandurangan AP, Meek K, Blundell TL, Ropars V, Calsou P, Charbonnier JB, Chaplin AK. Seif-El-Dahan M, et al. Among authors: britton s. Sci Adv. 2023 Jun 2;9(22):eadg2834. doi: 10.1126/sciadv.adg2834. Epub 2023 May 31. Sci Adv. 2023. PMID: 37256950 Free PMC article.
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J, Rak A, Legrand P, Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E, Britton S, Calsou P, Blundell TL, Varela PF, Chaplin AK, Charbonnier JB. Kefala Stavridi A, et al. Among authors: britton s. Nucleic Acids Res. 2023 Nov 27;51(21):11732-11747. doi: 10.1093/nar/gkad863. Nucleic Acids Res. 2023. PMID: 37870477 Free PMC article.
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.
Pinto LM, Pailas A, Bondarchenko M, Sharma AB, Neumann K, Rizzo AJ, Jeanty C, Nicot N, Racca C, Graham MK, Naughton C, Liu Y, Chen CL, Meakin PJ, Gilbert N, Britton S, Meeker AK, Heaphy CM, Larminat F, Van Dyck E. Pinto LM, et al. Among authors: britton s. Nucleic Acids Res. 2024 Feb 9;52(3):1136-1155. doi: 10.1093/nar/gkad1141. Nucleic Acids Res. 2024. PMID: 38038252 Free PMC article.
BRCA1 prevents R-loop-associated centromeric instability.
Racca C, Britton S, Hédouin S, Francastel C, Calsou P, Larminat F. Racca C, et al. Among authors: britton s. Cell Death Dis. 2021 Oct 1;12(10):896. doi: 10.1038/s41419-021-04189-3. Cell Death Dis. 2021. PMID: 34599155 Free PMC article.
Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Chebaiki M, Delfourne E, Tamhaev R, Danoun S, Rodriguez F, Hoffmann P, Grosjean E, Goncalves F, Azéma-Despeyroux J, Pál A, Korduláková J, Preuilh N, Britton S, Constant P, Marrakchi H, Maveyraud L, Mourey L, Lherbet C. Chebaiki M, et al. Among authors: britton s. Eur J Med Chem. 2023 Nov 5;259:115646. doi: 10.1016/j.ejmech.2023.115646. Epub 2023 Jul 16. Eur J Med Chem. 2023. PMID: 37482022
SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species.
Demange P, Joly E, Marcoux J, Zanon PRA, Listunov D, Rullière P, Barthes C, Noirot C, Izquierdo JB, Rozié A, Pradines K, Hee R, de Brito MV, Marcellin M, Serre RF, Bouchez O, Burlet-Schiltz O, Oliveira MCF, Ballereau S, Bernardes-Génisson V, Maraval V, Calsou P, Hacker SM, Génisson Y, Chauvin R, Britton S. Demange P, et al. Among authors: britton s. Elife. 2022 May 10;11:e73913. doi: 10.7554/eLife.73913. Elife. 2022. PMID: 35535493 Free PMC article.
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.
Bossuat M, Rullière P, Preuilh N, Peixoto A, Joly E, Gomez JG, Bourkhis M, Rodriguez F, Gonçalves F, Fabing I, Gaspard H, Bernardes-Génisson V, Maraval V, Ballereau S, Chauvin R, Britton S, Génisson Y. Bossuat M, et al. Among authors: britton s. J Med Chem. 2023 Oct 26;66(20):13918-13945. doi: 10.1021/acs.jmedchem.3c00859. Epub 2023 Oct 10. J Med Chem. 2023. PMID: 37816126
35 results