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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1974 2
1975 13
1976 5
1977 6
1978 10
1979 6
1980 26
1981 55
1982 71
1983 70
1984 103
1985 135
1986 127
1987 135
1988 136
1989 141
1990 130
1991 137
1992 153
1993 174
1994 167
1995 194
1996 196
1997 205
1998 244
1999 258
2000 290
2001 312
2002 319
2003 327
2004 390
2005 385
2006 388
2007 488
2008 524
2009 545
2010 582
2011 659
2012 625
2013 627
2014 634
2015 576
2016 367
2017 294
2018 434
2019 455
2020 485
2021 541
2022 484
2023 360
2024 54

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12,752 results

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Page 1
Reduced Number and Immune Dysfunction of CD4+ T Cells in Obesity Accelerate Colorectal Cancer Progression.
Yamada K, Saito M, Ando M, Abe T, Mukoyama T, Agawa K, Watanabe A, Takamura S, Fujita M, Urakawa N, Hasegawa H, Kanaji S, Matsuda T, Oshikiri T, Kakeji Y, Yamashita K. Yamada K, et al. Among authors: fujita m. Cells. 2022 Dec 25;12(1):86. doi: 10.3390/cells12010086. Cells. 2022. PMID: 36611881 Free PMC article.
We further established CD4+ T cell-depleted HFD-fed model mice, which showed reduced tumor infiltration, increased PD-1 expression in CD8+ T cells, and obesity-induced acceleration of tumor growth in a CD4+ T cell-dependent manner. These findings suggest that …
We further established CD4+ T cell-depleted HFD-fed model mice, which showed reduced tumor infiltration, increased PD-1 expression in …
Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy.
Sugimoto C, Fujita H, Wakao H. Sugimoto C, et al. Among authors: fujita h. Biomedicines. 2022 Dec 7;10(12):3160. doi: 10.3390/biomedicines10123160. Biomedicines. 2022. PMID: 36551916 Free PMC article. Review.
Mucosal-associated invariant T (MAIT) cells, a burgeoning type of the innate-like T cells, play a crucial role in maintaining immune homeostasis, particularly in host defense. Although many studies have implied the use of MAIT cells in tumor immunity, whether MAIT c …
Mucosal-associated invariant T (MAIT) cells, a burgeoning type of the innate-like T cells, play a crucial role in maintaining …
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity.
Luca D, Lee S, Hirota K, Okabe Y, Uehori J, Izawa K, Lanz AL, Schütte V, Sivri B, Tsukamoto Y, Hauck F, Behrendt R, Roers A, Fujita T, Nishikomori R, Lee-Kirsch MA, Kato H. Luca D, et al. Among authors: fujita t. Sci Adv. 2024 Mar;10(9):eadk0820. doi: 10.1126/sciadv.adk0820. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427731 Free PMC article.
We analyzed the underlying mechanisms using murine models and found that T(reg)-specific deletion of Adar1 caused peripheral T(reg) loss and scurfy-like lethal autoimmune disorders. Similarly, knock-in mice with T(reg)-specific expression of an MDA5 gain-of-f …
We analyzed the underlying mechanisms using murine models and found that T(reg)-specific deletion of Adar1 caused peripheral T
The Role of Interleukin-19 in Contact Hypersensitivity.
Fujimoto Y, Fujita T, Kuramoto N, Kuwamura M, Izawa T, Nishiyama K, Yoshida N, Nakajima H, Takeuchi T, Azuma YT. Fujimoto Y, et al. Among authors: fujita t. Biol Pharm Bull. 2018;41(2):182-189. doi: 10.1248/bpb.b17-00594. Biol Pharm Bull. 2018. PMID: 29386478 Free article.
The gastrointestinal tissues of IL-19 knockout mice show exacerbated experimental colitis mediated by the innate immune system and T cells. There is an increasing focus on the interaction and relationship of IL-19 with the function of T cells. Contact hypersensitivi …
The gastrointestinal tissues of IL-19 knockout mice show exacerbated experimental colitis mediated by the innate immune system and T
[Immunotherapy for refractory viral infections].
Morio T, Fujita Y, Takahashi S. Morio T, et al. Among authors: fujita y. Rinsho Ketsueki. 2018;59(2):205-215. doi: 10.11406/rinketsu.59.205. Rinsho Ketsueki. 2018. PMID: 29515076 Japanese.
Various antiviral agents have been developed, which are sometimes associated with toxicity, development of virus-resistant strain, and high cost. Virus-specific T-cell (VST) therapy provides an alternative curative therapy that can be effective for a prolonged time without …
Various antiviral agents have been developed, which are sometimes associated with toxicity, development of virus-resistant strain, and high …
Human T-lymphotropic virus type I provirus and T-cell prolymphocytic leukemia.
Kojima K, Hara M, Sawada T, Miyata A, Saito H, Matsuo Y, Yasukawa M, Fujita S, Harada M. Kojima K, et al. Among authors: fujita s. Leuk Lymphoma. 2000 Jul;38(3-4):381-6. doi: 10.3109/10428190009087029. Leuk Lymphoma. 2000. PMID: 10830745 Review.
T-cell prolymphocytic leukemia (T-PLL) is a rare type of post-thymic T-cell neoplasm, the etiology of which is unknown. Patients with T-PLL have been found to be seronegative for human T-lymphotropic virus type-I (HTLV-I), and their leukemia cel
T-cell prolymphocytic leukemia (T-PLL) is a rare type of post-thymic T-cell neoplasm, the etiology of which is unknown.
LAT1-specific inhibitor ameliorates severe autoimmune arthritis in SKG mouse.
Owada T, Kurasawa K, Endou H, Fujita T, Anzai N, Hayashi K. Owada T, et al. Among authors: fujita t. Int Immunopharmacol. 2022 Aug;109:108817. doi: 10.1016/j.intimp.2022.108817. Epub 2022 May 11. Int Immunopharmacol. 2022. PMID: 35561482
LAT1 is an attractive therapeutic target for treating overactive T cell-mediated immune disorders due to its high expression in activated T cells, but not in resting T cells. Here, we demonstrate that LAT1 plays a crucial role in T helper (Th) 17-media …
LAT1 is an attractive therapeutic target for treating overactive T cell-mediated immune disorders due to its high expression in activ …
Phase diagram of Bi2Sr2CaCu2O8+δ revisited.
Drozdov IK, Pletikosić I, Kim CK, Fujita K, Gu GD, Davis JCS, Johnson PD, Božović I, Valla T. Drozdov IK, et al. Among authors: fujita k. Nat Commun. 2018 Dec 6;9(1):5210. doi: 10.1038/s41467-018-07686-w. Nat Commun. 2018. PMID: 30523265 Free PMC article.
In most materials, p cannot be determined from the chemical composition, but it is derived from the superconducting transition temperature, T(c), using the assumption that the T(c) dependence on doping is universal. ...In the highly overdoped regime, the superconduc …
In most materials, p cannot be determined from the chemical composition, but it is derived from the superconducting transition temperature, …
Mucosal-associated invariant T cells from induced pluripotent stem cells: A novel approach for modeling human diseases.
Sugimoto C, Fujita H, Wakao H. Sugimoto C, et al. Among authors: fujita h. World J Stem Cells. 2016 Apr 26;8(4):158-69. doi: 10.4252/wjsc.v8.i4.158. World J Stem Cells. 2016. PMID: 27114747 Free PMC article. Review.
However, if mice are deficient in certain cells and/or effectors associated with human diseases, how can their functions be investigated in this species? Mucosal-associated invariant T (MAIT) cells, a novel innate-like T cell family member, are a good example. MAIT …
However, if mice are deficient in certain cells and/or effectors associated with human diseases, how can their functions be investigated in …
12,752 results
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