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Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions.
Thiem K, Hoeke G, Zhou E, Hijmans A, Houben T, Boels MG, Mol IM, Lutgens E, Shiri-Sverdlov R, Bussink J, Kanneganti TD, Boon MR, Stienstra R, Tack CJ, Rensen PC, Netea MG, Berbée JF, van Diepen JA. Thiem K, et al. Among authors: tack cj. Diab Vasc Dis Res. 2020 Jan-Feb;17(1):1479164119892140. doi: 10.1177/1479164119892140. Epub 2019 Dec 23. Diab Vasc Dis Res. 2020. PMID: 31868000 Free PMC article.
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.
Netea MG, Joosten LA, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, Tack CJ, van Krieken H, Kim SH, Stalenhoef AF, van de Loo FA, Verschueren I, Pulawa L, Akira S, Eckel RH, Dinarello CA, van den Berg W, van der Meer JW. Netea MG, et al. Among authors: tack cj. Nat Med. 2006 Jun;12(6):650-6. doi: 10.1038/nm1415. Epub 2006 May 28. Nat Med. 2006. PMID: 16732281
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
Stienstra R, Joosten LA, Koenen T, van Tits B, van Diepen JA, van den Berg SA, Rensen PC, Voshol PJ, Fantuzzi G, Hijmans A, Kersten S, Müller M, van den Berg WB, van Rooijen N, Wabitsch M, Kullberg BJ, van der Meer JW, Kanneganti T, Tack CJ, Netea MG. Stienstra R, et al. Among authors: tack cj. Cell Metab. 2010 Dec 1;12(6):593-605. doi: 10.1016/j.cmet.2010.11.011. Cell Metab. 2010. PMID: 21109192 Free PMC article.
Treatment with Anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study.
van Asseldonk EJ, Stienstra R, Koenen TB, Joosten LA, Netea MG, Tack CJ. van Asseldonk EJ, et al. Among authors: tack cj. J Clin Endocrinol Metab. 2011 Jul;96(7):2119-26. doi: 10.1210/jc.2010-2992. Epub 2011 Apr 20. J Clin Endocrinol Metab. 2011. PMID: 21508140 Free article. Clinical Trial.
The inflammasome and caspase-1 activation: a new mechanism underlying increased inflammatory activity in human visceral adipose tissue.
Koenen TB, Stienstra R, van Tits LJ, Joosten LA, van Velzen JF, Hijmans A, Pol JA, van der Vliet JA, Netea MG, Tack CJ, Stalenhoef AF, de Graaf J. Koenen TB, et al. Among authors: tack cj. Endocrinology. 2011 Oct;152(10):3769-78. doi: 10.1210/en.2010-1480. Epub 2011 Aug 23. Endocrinology. 2011. PMID: 21862623 Free article.
Inflammasome is a central player in the induction of obesity and insulin resistance.
Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, Kanneganti TD. Stienstra R, et al. Among authors: tack cj. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15324-9. doi: 10.1073/pnas.1100255108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876127 Free PMC article.
285 results