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Page 1
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.
Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone TM, Hickman AR, Mao W, Thakar T, Vaitsiankova A, Huang JW, Cuella-Martin R, Hayward SB, Kesner JS, Ghasemzadeh A, Nambiar TS, Ho P, Rialdi A, Hebrard M, Li Y, Gao J, Gopinath S, Adeleke OA, Venters BJ, Drake CG, Baer R, Izar B, Guccione E, Keogh MC, Guerois R, Sun L, Lu C, Califano A, Ciccia A. Leuzzi G, et al. Among authors: taglialatela a. Cell. 2024 Feb 15;187(4):861-881.e32. doi: 10.1016/j.cell.2024.01.008. Epub 2024 Jan 31. Cell. 2024. PMID: 38301646
Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB. Schvartzman JM, et al. Among authors: taglialatela a. Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12. Mol Cell. 2023. PMID: 37311462
Replication stress impairs chromosome segregation and preimplantation development in human embryos.
Palmerola KL, Amrane S, De Los Angeles A, Xu S, Wang N, de Pinho J, Zuccaro MV, Taglialatela A, Massey DJ, Turocy J, Robles A, Subbiah A, Prosser B, Lobo R, Ciccia A, Koren A, Baslan T, Egli D. Palmerola KL, et al. Among authors: taglialatela a. Cell. 2022 Aug 4;185(16):2988-3007.e20. doi: 10.1016/j.cell.2022.06.028. Epub 2022 Jul 19. Cell. 2022. PMID: 35858625 Free article.
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
Lee J, Lee J, Sohn EJ, Taglialatela A, O'Sullivan RJ, Ciccia A, Min J. Lee J, et al. Among authors: taglialatela a. bioRxiv [Preprint]. 2023 Oct 23:2023.07.31.551186. doi: 10.1101/2023.07.31.551186. bioRxiv. 2023. PMID: 37577643 Free PMC article. Preprint.
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer.
Filippone MG, Gaglio D, Bonfanti R, Tucci FA, Ceccacci E, Pennisi R, Bonanomi M, Jodice G, Tillhon M, Montani F, Bertalot G, Freddi S, Vecchi M, Taglialatela A, Romanenghi M, Romeo F, Bianco N, Munzone E, Sanguedolce F, Vago G, Viale G, Di Fiore PP, Minucci S, Alberghina L, Colleoni M, Veronesi P, Tosoni D, Pece S. Filippone MG, et al. Among authors: taglialatela a. Nat Commun. 2022 May 12;13(1):2642. doi: 10.1038/s41467-022-30375-8. Nat Commun. 2022. PMID: 35550508 Free PMC article. Clinical Trial.
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Taglialatela A, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK. Wang YC, et al. Among authors: taglialatela a. Cell Rep. 2023 Apr 25;42(4):112296. doi: 10.1016/j.celrep.2023.112296. Epub 2023 Mar 23. Cell Rep. 2023. PMID: 36961817 Free PMC article.
CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue.
Gu J, Iyer A, Wesley B, Taglialatela A, Leuzzi G, Hangai S, Decker A, Gu R, Klickstein N, Shuai Y, Jankovic K, Parker-Burns L, Jin Y, Zhang JY, Hong J, Niu S, Chou J, Landau DA, Azizi E, Chan EM, Ciccia A, Gaublomme JT. Gu J, et al. Among authors: taglialatela a. bioRxiv [Preprint]. 2023 Dec 26:2023.12.26.572587. doi: 10.1101/2023.12.26.572587. bioRxiv. 2023. PMID: 38234835 Free PMC article. Preprint.
HATtracting Nucleases to Stalled Forks.
Leuzzi G, Taglialatela A, Ciccia A. Leuzzi G, et al. Among authors: taglialatela a. Mol Cell. 2020 Oct 15;80(2):177-180. doi: 10.1016/j.molcel.2020.09.031. Mol Cell. 2020. PMID: 33065018 Free article.
19 results