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Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells.
Iizuka-Ohashi M, Watanabe M, Sukeno M, Morita M, Hoang NTH, Kuchimaru T, Kizaka-Kondoh S, Sowa Y, Sakaguchi K, Taguchi T, Sakai T. Iizuka-Ohashi M, et al. Among authors: taguchi t. Oncotarget. 2018 Apr 13;9(28):19597-19612. doi: 10.18632/oncotarget.24696. eCollection 2018 Apr 13. Oncotarget. 2018. PMID: 29731968 Free PMC article.
The histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth of triple-negative breast cancer cells with the suppression of survivin, Bcl-xL, and the MAPK pathway.
Ono H, Sowa Y, Horinaka M, Iizumi Y, Watanabe M, Morita M, Nishimoto E, Taguchi T, Sakai T. Ono H, et al. Among authors: taguchi t. Breast Cancer Res Treat. 2018 Aug;171(1):43-52. doi: 10.1007/s10549-018-4815-x. Epub 2018 May 11. Breast Cancer Res Treat. 2018. PMID: 29752686
Plasmalogen Deficiency and Overactive Fatty Acid Elongation Biomarkers in Serum of Breast Cancer Patients Pre- and Post-Surgery-New Insights on Diagnosis, Risk Assessment, and Disease Mechanisms.
Tomida S, Goodenowe DB, Koyama T, Ozaki E, Kuriyama N, Morita M, Yamazaki Y, Sakaguchi K, Uehara R, Taguchi T. Tomida S, et al. Among authors: taguchi t. Cancers (Basel). 2021 Aug 19;13(16):4170. doi: 10.3390/cancers13164170. Cancers (Basel). 2021. PMID: 34439324 Free PMC article.
Oxidative stress induces EGFR inhibition-related skin cell death.
Morita M, Iizuka-Ohashi M, Watanabe M, Narita T, Kato C, Kakibuchi D, Kitano F, Ouchi Y, Sakaguchi K, Taguchi T. Morita M, et al. Among authors: taguchi t. J Clin Biochem Nutr. 2021 May;68(3):235-242. doi: 10.3164/jcbn.20-112. Epub 2021 Mar 25. J Clin Biochem Nutr. 2021. PMID: 34025026 Free PMC article.
2,927 results