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Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity.
Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Horike N, Yoneda M, Ohno H, Tsuchiya Y, Kamata H, Tahara H, Isobe T, Nishimura F, Katagiri H, Oka Y, Fukushima T, Takahashi SI, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: tahara h. J Biol Chem. 2010 Oct 22;285(43):33018-33027. doi: 10.1074/jbc.M110.137836. Epub 2010 Jul 30. J Biol Chem. 2010. PMID: 20675384 Free PMC article.
miR-22 represses cancer progression by inducing cellular senescence.
Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Matsunaga J, Takahashi RU, Takata T, Shimamoto A, Ochiya T, Tahara H. Xu D, et al. Among authors: tahara h. J Cell Biol. 2011 Apr 18;193(2):409-24. doi: 10.1083/jcb.201010100. J Cell Biol. 2011. PMID: 21502362 Free PMC article.
Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.
Shiotani B, Nguyen HD, Håkansson P, Maréchal A, Tse A, Tahara H, Zou L. Shiotani B, et al. Among authors: tahara h. Cell Rep. 2013 May 30;3(5):1651-62. doi: 10.1016/j.celrep.2013.04.018. Epub 2013 May 16. Cell Rep. 2013. PMID: 23684611 Free PMC article.
DSE-FRET: A new anticancer drug screening assay for DNA binding proteins.
Miyagi T, Shiotani B, Miyoshi R, Yamamoto T, Oka T, Umezawa K, Ochiya T, Takano M, Tahara H. Miyagi T, et al. Among authors: tahara h. Cancer Sci. 2014 Jul;105(7):870-4. doi: 10.1111/cas.12420. Epub 2014 May 14. Cancer Sci. 2014. PMID: 24724610 Free PMC article.
Targeting DNA binding proteins for cancer therapy.
Shiroma Y, Takahashi RU, Yamamoto Y, Tahara H. Shiroma Y, et al. Among authors: tahara h. Cancer Sci. 2020 Apr;111(4):1058-1064. doi: 10.1111/cas.14355. Epub 2020 Mar 24. Cancer Sci. 2020. PMID: 32073717 Free PMC article. Review.
758 results