Tain LS - Search Results

1

Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production.

Tain LS, Jain C, Nespital T, Froehlich J, Hinze Y, Grönke S, Partridge L. Tain LS, et al. Aging Cell. 2020 Jan;19(1):e13043. doi: 10.1111/acel.13043. Epub 2019 Nov 13. Aging Cell. 2020. PMID: 31721422 Free PMC article.

2

MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals.

Wredenberg A, Lagouge M, Bratic A, Metodiev MD, Spåhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, Habermann B, Partridge L, Park CB, Larsson NG. Wredenberg A, et al. PLoS Genet. 2013;9(1):e1003178. doi: 10.1371/journal.pgen.1003178. Epub 2013 Jan 3. PLoS Genet. 2013. PMID: 23300484 Free PMC article.

3

Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila.

Metaxakis A, Tain LS, Grönke S, Hendrich O, Hinze Y, Birras U, Partridge L. Metaxakis A, et al. Among authors: tain ls. PLoS Biol. 2014 Apr 1;12(4):e1001824. doi: 10.1371/journal.pbio.1001824. eCollection 2014 Apr. PLoS Biol. 2014. PMID: 24690889 Free PMC article.

4

Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease.

Sofola-Adesakin O, Castillo-Quan JI, Rallis C, Tain LS, Bjedov I, Rogers I, Li L, Martinez P, Khericha M, Cabecinha M, Bähler J, Partridge L. Sofola-Adesakin O, et al. Among authors: tain ls. Front Aging Neurosci. 2014 Jul 30;6:190. doi: 10.3389/fnagi.2014.00190. eCollection 2014. Front Aging Neurosci. 2014. PMID: 25126078 Free PMC article.

5

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation.

Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG. Baggio F, et al. Among authors: tain ls. Nucleic Acids Res. 2014 Dec 16;42(22):13920-38. doi: 10.1093/nar/gku1132. Epub 2014 Nov 26. Nucleic Acids Res. 2014. PMID: 25428350 Free PMC article.

6

Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila.

Afschar S, Toivonen JM, Hoffmann JM, Tain LS, Wieser D, Finlayson AJ, Driege Y, Alic N, Emran S, Stinn J, Froehlich J, Piper MD, Partridge L. Afschar S, et al. Among authors: tain ls. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1321-6. doi: 10.1073/pnas.1515137113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787908 Free PMC article.

7

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.

Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Castillo-Quan JI, et al. Among authors: tain ls. Cell Rep. 2016 Apr 19;15(3):638-650. doi: 10.1016/j.celrep.2016.03.041. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068460 Free PMC article.

8

Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice.

Essers P, Tain LS, Nespital T, Goncalves J, Froehlich J, Partridge L. Essers P, et al. Among authors: tain ls. Sci Rep. 2016 Jul 25;6:30290. doi: 10.1038/srep30290. Sci Rep. 2016. PMID: 27452396 Free PMC article.

9

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila.

Brandt T, Mourier A, Tain LS, Partridge L, Larsson NG, Kühlbrandt W. Brandt T, et al. Among authors: tain ls. Elife. 2017 Jul 12;6:e24662. doi: 10.7554/eLife.24662. Elife. 2017. PMID: 28699890 Free PMC article.

10

A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.

Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L. Tain LS, et al. Mol Syst Biol. 2017 Sep 15;13(9):939. doi: 10.15252/msb.20177663. Mol Syst Biol. 2017. PMID: 28916541 Free PMC article.

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