Takahashi H - Search Results

1

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.

Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu AH, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM, Cox NJ, Altman RB, Klein TE, Nakamura Y, Johnson JA. Perera MA, et al. Among authors: takahashi h. Lancet. 2013 Aug 31;382(9894):790-6. doi: 10.1016/S0140-6736(13)60681-9. Epub 2013 Jun 5. Lancet. 2013. PMID: 23755828 Free PMC article.

2

Novel single nucleotide polymorphism in CYP2C9 is associated with changes in warfarin clearance and CYP2C9 expression levels in African Americans.

Hernandez W, Aquino-Michaels K, Drozda K, Patel S, Jeong Y, Takahashi H, Cavallari LH, Perera MA. Hernandez W, et al. Among authors: takahashi h. Transl Res. 2015 Jun;165(6):651-7. doi: 10.1016/j.trsl.2014.11.006. Epub 2014 Nov 22. Transl Res. 2015. PMID: 25499099 Free PMC article.

3

CYP2C9 promoter region single-nucleotide polymorphisms linked to the R150H polymorphism are functional suggesting their role in CYP2C9*8-mediated effects.

Cavallari LH, Vaynshteyn D, Freeman KM, Wang D, Perera MA, Takahashi H, Drozda K, Patel SR, Jeong H. Cavallari LH, et al. Among authors: takahashi h. Pharmacogenet Genomics. 2013 Apr;23(4):228-31. doi: 10.1097/FPC.0b013e32835e95c7. Pharmacogenet Genomics. 2013. PMID: 23376925 Free PMC article.

4

Factors influencing pharmacokinetics of warfarin in African-Americans: implications for pharmacogenetic dosing algorithms.

Nagai R, Ohara M, Cavallari LH, Drozda K, Patel SR, Nutescu EA, Perera MA, Hernandez W, Kaneko N, Hibiya M, Takahashi H. Nagai R, et al. Among authors: takahashi h. Pharmacogenomics. 2015;16(3):217-25. doi: 10.2217/pgs.14.160. Pharmacogenomics. 2015. PMID: 25712185 Free PMC article.

5

Differences in Warfarin Pharmacodynamics and Predictors of Response Among Three Racial Populations.

Ohara M, Suzuki Y, Shinohara S, Gong IY, Schmerk CL, Tirona RG, Schwarz UI, Wen MS, Lee MTM, Mihara K, Nutescu EA, Perera MA, Cavallari LH, Kim RB, Takahashi H. Ohara M, et al. Among authors: takahashi h. Clin Pharmacokinet. 2019 Aug;58(8):1077-1089. doi: 10.1007/s40262-019-00745-5. Clin Pharmacokinet. 2019. PMID: 30815847

6

Correlations between the enantio- and regio-selective metabolisms of warfarin.

Takahashi H, Ohara M, Shibata S, Lee MT, Cavallari LH, Nutescu EA, Scordo MG, Pengo V, Padrini R, Atsuda K, Matsubara H, Chen YT, Echizen H. Takahashi H, et al. Pharmacogenomics. 2017 Jan;18(2):133-142. doi: 10.2217/pgs-2016-0149. Epub 2016 Dec 20. Pharmacogenomics. 2017. PMID: 27995809

7

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.

Takahashi H, Wilkinson GR, Nutescu EA, Morita T, Ritchie MD, Scordo MG, Pengo V, Barban M, Padrini R, Ieiri I, Otsubo K, Kashima T, Kimura S, Kijima S, Echizen H. Takahashi H, et al. Pharmacogenet Genomics. 2006 Feb;16(2):101-10. doi: 10.1097/01.fpc.0000184955.08453.a8. Pharmacogenet Genomics. 2006. PMID: 16424822

8

[Warfarin resistance and related pharmacogenetic information].

Takahashi H. Takahashi H. Brain Nerve. 2008 Nov;60(11):1365-71. Brain Nerve. 2008. PMID: 19069171 Review. Japanese.

9

Inter-individual differences in baseline coagulation activities and their implications for international normalized ratio control during warfarin initiation therapy.

Ichimura Y, Takahashi H, Lee MT, Shiomi M, Mihara K, Morita T, Chen YT, Echizen H. Ichimura Y, et al. Among authors: takahashi h. Clin Pharmacokinet. 2012 Dec;51(12):799-808. doi: 10.1007/s40262-012-0009-6. Clin Pharmacokinet. 2012. PMID: 23018470 Clinical Trial.

10

5'-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients.

Takahashi H, Ieiri I, Wilkinson GR, Mayo G, Kashima T, Kimura S, Otsubo K, Echizen H. Takahashi H, et al. Blood. 2004 Apr 15;103(8):3055-7. doi: 10.1182/blood-2003-07-2521. Epub 2003 Dec 30. Blood. 2004. PMID: 15070684 Free article.

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