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Lack of hepatocarcinogenicity of 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-oxirane, 3-hydroxy-2-naphthoic acid, and acetoacetanilide in a medium-term rat liver bioassay.
Yamagata H, Saito T, Okamoto T, Satomoto K, Mitsumoto T, Wakita A, Nakamura M, Hayashi T, Kuroiwa Y. Yamagata H, et al. Among authors: okamoto t. J Toxicol Pathol. 2022 Oct;35(4):313-320. doi: 10.1293/tox.2022-0010. Epub 2022 Aug 1. J Toxicol Pathol. 2022. PMID: 36406173 Free PMC article.
Hepatocyte proliferation activity in untreated rats, measured by immunohistochemical detection of Ki-67: The effect of age on the repeated-dose liver micronucleus assay.
Satomoto K, Aoki M, Wakita A, Yamagata H, Mitsumoto T, Okamoto T, Harada R, Hamada S. Satomoto K, et al. Among authors: okamoto t. Mutat Res Genet Toxicol Environ Mutagen. 2023 Aug-Sep;890:503658. doi: 10.1016/j.mrgentox.2023.503658. Epub 2023 Jul 10. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 37567645