Tan PK - Search Results

1

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.

Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. Miner JN, et al. Among authors: tan pk. Arthritis Res Ther. 2016 Oct 3;18(1):214. doi: 10.1186/s13075-016-1107-x. Arthritis Res Ther. 2016. PMID: 27716403 Free PMC article. Clinical Trial.

2

Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout.

Tan PK, Farrar JE, Gaucher EA, Miner JN. Tan PK, et al. Mol Biol Evol. 2016 Sep;33(9):2193-200. doi: 10.1093/molbev/msw116. Epub 2016 Jun 26. Mol Biol Evol. 2016. PMID: 27352852 Free PMC article.

3

Mechanism of high affinity inhibition of the human urate transporter URAT1.

Tan PK, Ostertag TM, Miner JN. Tan PK, et al. Sci Rep. 2016 Oct 7;6:34995. doi: 10.1038/srep34995. Sci Rep. 2016. PMID: 27713539 Free PMC article.

4

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.

Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. Miner JN, et al. Among authors: tan pk. Arthritis Res Ther. 2016 Oct 12;18(1):236. doi: 10.1186/s13075-016-1150-7. Arthritis Res Ther. 2016. PMID: 27733209 Free PMC article. No abstract available.

5

Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout.

Tan PK, Liu S, Gunic E, Miner JN. Tan PK, et al. Sci Rep. 2017 Apr 6;7(1):665. doi: 10.1038/s41598-017-00706-7. Sci Rep. 2017. PMID: 28386072 Free PMC article.

6

Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis.

Tan PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, Aidnik H, Linker S, Murphy K, Miner JN, Brenner DA. Tan PK, et al. Am J Pathol. 2024 Mar;194(3):353-368. doi: 10.1016/j.ajpath.2023.12.005. Epub 2023 Dec 28. Am J Pathol. 2024. PMID: 38158078

7

Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer.

Tan PK, Wang J, Littler PL, Wong KK, Sweetnam TA, Keefe W, Nash NR, Reding EC, Piu F, Brann MR, Schiffer HH. Tan PK, et al. Mol Pharmacol. 2007 Dec;72(6):1440-6. doi: 10.1124/mol.107.039636. Epub 2007 Aug 22. Mol Pharmacol. 2007. PMID: 17715395

8

Distinct Lateral Prefrontal Regions Are Organized in an Anterior-Posterior Functional Gradient.

Tan PK, Tang C, Herikstad R, Pillay A, Libedinsky C. Tan PK, et al. J Neurosci. 2023 Sep 20;43(38):6564-6572. doi: 10.1523/JNEUROSCI.0007-23.2023. Epub 2023 Aug 22. J Neurosci. 2023. PMID: 37607819 Free PMC article.

9

Emerging Strategies to Improve the Stability and Bioavailability of Insulin: An Update on Formulations and Delivery Approaches.

Tan PK, Kuppusamy UR, Chua KH, Arumugam B. Tan PK, et al. Curr Drug Deliv. 2023;20(8):1141-1162. doi: 10.2174/1567201820666221102094433. Curr Drug Deliv. 2023. PMID: 36330644 Review.

10

Role of surface-exposed charged basic amino acids (Lys, Arg) and guanidination in insulin on the interaction and stability of insulin-insulin receptor complex.

Lee VS, Sukumaran SD, Tan PK, Kuppusamy UR, Arumugam B. Lee VS, et al. Among authors: tan pk. Comput Biol Chem. 2021 Jun;92:107501. doi: 10.1016/j.compbiolchem.2021.107501. Epub 2021 Apr 24. Comput Biol Chem. 2021. PMID: 33989998

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