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Editorial: Epigenetics and cellular plasticity in glioblastoma.
Lo HW, Tapinos N. Lo HW, et al. Among authors: tapinos n. Front Oncol. 2023 Mar 20;13:1179214. doi: 10.3389/fonc.2023.1179214. eCollection 2023. Front Oncol. 2023. PMID: 37020873 Free PMC article. No abstract available.
Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosis.
Borsuk R, Zhou L, Chang WI, Zhang Y, Sharma A, Prabhu VV, Tapinos N, Lulla RR, El-Deiry WS. Borsuk R, et al. Among authors: tapinos n. Am J Cancer Res. 2021 Sep 15;11(9):4607-4623. eCollection 2021. Am J Cancer Res. 2021. PMID: 34659909 Free PMC article.
EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG.
Zhang Y, Zhou L, Safran H, Borsuk R, Lulla R, Tapinos N, Seyhan AA, El-Deiry WS. Zhang Y, et al. Among authors: tapinos n. Neoplasia. 2021 Aug;23(8):792-810. doi: 10.1016/j.neo.2021.06.007. Epub 2021 Jul 8. Neoplasia. 2021. PMID: 34246076 Free PMC article.
miRNA-mediated loss of m6A increases nascent translation in glioblastoma.
Zepecki JP, Karambizi D, Fajardo JE, Snyder KM, Guetta-Terrier C, Tang OY, Chen JS, Sarkar A, Fiser A, Toms SA, Tapinos N. Zepecki JP, et al. Among authors: tapinos n. PLoS Genet. 2021 Mar 8;17(3):e1009086. doi: 10.1371/journal.pgen.1009086. eCollection 2021 Mar. PLoS Genet. 2021. PMID: 33684100 Free PMC article.
35 results