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Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.
Clapper JR, Moreno-Sanz G, Russo R, Guijarro A, Vacondio F, Duranti A, Tontini A, Sanchini S, Sciolino NR, Spradley JM, Hohmann AG, Calignano A, Mor M, Tarzia G, Piomelli D. Clapper JR, et al. Among authors: tarzia g. Nat Neurosci. 2010 Oct;13(10):1265-70. doi: 10.1038/nn.2632. Epub 2010 Sep 19. Nat Neurosci. 2010. PMID: 20852626 Free PMC article.
An endocannabinoid mechanism for stress-induced analgesia.
Hohmann AG, Suplita RL, Bolton NM, Neely MH, Fegley D, Mangieri R, Krey JF, Walker JM, Holmes PV, Crystal JD, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. Hohmann AG, et al. Among authors: tarzia g. Nature. 2005 Jun 23;435(7045):1108-12. doi: 10.1038/nature03658. Nature. 2005. PMID: 15973410 Free article.
Modulation of anxiety through blockade of anandamide hydrolysis.
Kathuria S, Gaetani S, Fegley D, Valiño F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A, Tattoli M, Palmery M, Cuomo V, Piomelli D. Kathuria S, et al. Among authors: tarzia g. Nat Med. 2003 Jan;9(1):76-81. doi: 10.1038/nm803. Epub 2002 Dec 2. Nat Med. 2003. PMID: 12461523
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).
Piomelli D, Tarzia G, Duranti A, Tontini A, Mor M, Compton TR, Dasse O, Monaghan EP, Parrott JA, Putman D. Piomelli D, et al. Among authors: tarzia g. CNS Drug Rev. 2006 Spring;12(1):21-38. doi: 10.1111/j.1527-3458.2006.00021.x. CNS Drug Rev. 2006. PMID: 16834756 Free PMC article. Review.
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.
Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. Russo R, et al. Among authors: tarzia g. J Pharmacol Exp Ther. 2007 Jul;322(1):236-42. doi: 10.1124/jpet.107.119941. Epub 2007 Apr 5. J Pharmacol Exp Ther. 2007. PMID: 17412883
147 results