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Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.
Taschner M, Basquin J, Steigenberger B, Schäfer IB, Soh YM, Basquin C, Lorentzen E, Räschle M, Scheltema RA, Gruber S. Taschner M, et al. EMBO J. 2021 Aug 2;40(15):e107807. doi: 10.15252/embj.2021107807. Epub 2021 Jun 30. EMBO J. 2021. PMID: 34191293 Free PMC article.
Structural basis for plasmid restriction by SMC JET nuclease.
Roisné-Hamelin F, Liu HW, Taschner M, Li Y, Gruber S. Roisné-Hamelin F, et al. Among authors: taschner m. Mol Cell. 2024 Mar 7;84(5):883-896.e7. doi: 10.1016/j.molcel.2024.01.009. Epub 2024 Feb 2. Mol Cell. 2024. PMID: 38309275
DNA segment capture by Smc5/6 holocomplexes.
Taschner M, Gruber S. Taschner M, et al. Nat Struct Mol Biol. 2023 May;30(5):619-628. doi: 10.1038/s41594-023-00956-2. Epub 2023 Apr 3. Nat Struct Mol Biol. 2023. PMID: 37012407 Free PMC article.
Self-organization of parS centromeres by the ParB CTP hydrolase.
Soh YM, Davidson IF, Zamuner S, Basquin J, Bock FP, Taschner M, Veening JW, De Los Rios P, Peters JM, Gruber S. Soh YM, et al. Among authors: taschner m. Science. 2019 Nov 29;366(6469):1129-1133. doi: 10.1126/science.aay3965. Epub 2019 Oct 24. Science. 2019. PMID: 31649139 Free PMC article.
A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection.
Liu X, Van Maele L, Matarazzo L, Soulard D, Alves Duarte da Silva V, de Bakker V, Dénéréaz J, Bock FP, Taschner M, Ou J, Gruber S, Nizet V, Sirard JC, Veening JW. Liu X, et al. Among authors: taschner m. Cell Host Microbe. 2024 Mar 13;32(3):304-314.e8. doi: 10.1016/j.chom.2024.02.002. Epub 2024 Feb 27. Cell Host Microbe. 2024. PMID: 38417443
Essential role of Cp190 in physical and regulatory boundary formation.
Kaushal A, Dorier J, Wang B, Mohana G, Taschner M, Cousin P, Waridel P, Iseli C, Semenova A, Restrepo S, Guex N, Aiden EL, Gambetta MC. Kaushal A, et al. Among authors: taschner m. Sci Adv. 2022 May 13;8(19):eabl8834. doi: 10.1126/sciadv.abl8834. Epub 2022 May 13. Sci Adv. 2022. PMID: 35559678 Free PMC article.
CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions.
Kaushal A, Mohana G, Dorier J, Özdemir I, Omer A, Cousin P, Semenova A, Taschner M, Dergai O, Marzetta F, Iseli C, Eliaz Y, Weisz D, Shamim MS, Guex N, Lieberman Aiden E, Gambetta MC. Kaushal A, et al. Among authors: taschner m. Nat Commun. 2021 Feb 12;12(1):1011. doi: 10.1038/s41467-021-21366-2. Nat Commun. 2021. PMID: 33579945 Free PMC article.
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