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Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors.
Schiefer IT, Tapadar S, Litosh V, Siklos M, Scism R, Wijewickrama GT, Chandrasena EP, Sinha V, Tavassoli E, Brunsteiner M, Fa' M, Arancio O, Petukhov P, Thatcher GR. Schiefer IT, et al. Among authors: tavassoli e. J Med Chem. 2013 Aug 8;56(15):6054-68. doi: 10.1021/jm4006719. Epub 2013 Jul 22. J Med Chem. 2013. PMID: 23834438 Free PMC article.
Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia.
Luo J, Lee SH, VandeVrede L, Qin Z, Piyankarage S, Tavassoli E, Asghodom RT, Ben Aissa M, Fà M, Arancio O, Yue L, Pepperberg DR, Thatcher GR. Luo J, et al. Among authors: tavassoli e. BMC Neurosci. 2015 Oct 19;16:67. doi: 10.1186/s12868-015-0208-9. BMC Neurosci. 2015. PMID: 26480871 Free PMC article.
Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase.
Morfini GA, Bosco DA, Brown H, Gatto R, Kaminska A, Song Y, Molla L, Baker L, Marangoni MN, Berth S, Tavassoli E, Bagnato C, Tiwari A, Hayward LJ, Pigino GF, Watterson DM, Huang CF, Banker G, Brown RH Jr, Brady ST. Morfini GA, et al. Among authors: tavassoli e. PLoS One. 2013 Jun 12;8(6):e65235. doi: 10.1371/journal.pone.0065235. Print 2013. PLoS One. 2013. PMID: 23776455 Free PMC article.
31 results