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Page 1
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Mukadam AS, Miller LVC, Smith AE, Vaysburd M, Sakya SA, Sanford S, Keeling S, Tuck BJ, Katsinelos T, Green C, Skov L, Kaalund SS, Foss S, Mayes K, O'Connell K, Wing M, Knox C, Banbury J, Avezov E, Rowe JB, Goedert M, Andersen JT, James LC, McEwan WA. Mukadam AS, et al. Among authors: katsinelos t. Science. 2023 Mar 31;379(6639):1336-1341. doi: 10.1126/science.abn1366. Epub 2023 Mar 30. Science. 2023. PMID: 36996217 Free PMC article.
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding.
Dimou E, Katsinelos T, Meisl G, Tuck BJ, Keeling S, Smith AE, Hidari E, Lam JYL, Burke M, Lövestam S, Ranasinghe RT, McEwan WA, Klenerman D. Dimou E, et al. Among authors: katsinelos t. Cell Rep. 2023 Jul 25;42(7):112725. doi: 10.1016/j.celrep.2023.112725. Epub 2023 Jul 1. Cell Rep. 2023. PMID: 37393617 Free PMC article.
Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation.
Darricau M, Dou C, Kinet R, Zhu T, Zhou L, Li X, Bedel A, Claverol S, Tokarski C, Katsinelos T, McEwan WA, Zhang L, Gao R, Bourdenx M, Dehay B, Qin C, Bezard E, Planche V. Darricau M, et al. Among authors: katsinelos t. Alzheimers Dement. 2024 Mar;20(3):1894-1912. doi: 10.1002/alz.13604. Epub 2023 Dec 26. Alzheimers Dement. 2024. PMID: 38148705 Free PMC article.
Unconventional Secretion Mediates the Trans-cellular Spreading of Tau.
Katsinelos T, Zeitler M, Dimou E, Karakatsani A, Müller HM, Nachman E, Steringer JP, Ruiz de Almodovar C, Nickel W, Jahn TR. Katsinelos T, et al. Cell Rep. 2018 May 15;23(7):2039-2055. doi: 10.1016/j.celrep.2018.04.056. Cell Rep. 2018. PMID: 29768203 Free article.
Single event visualization of unconventional secretion of FGF2.
Dimou E, Cosentino K, Platonova E, Ros U, Sadeghi M, Kashyap P, Katsinelos T, Wegehingel S, Noé F, García-Sáez AJ, Ewers H, Nickel W. Dimou E, et al. Among authors: katsinelos t. J Cell Biol. 2019 Feb 4;218(2):683-699. doi: 10.1083/jcb.201802008. Epub 2018 Nov 23. J Cell Biol. 2019. PMID: 30470711 Free PMC article.
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Tuck BJ, Miller LVC, Katsinelos T, Smith AE, Wilson EL, Keeling S, Cheng S, Vaysburd MJ, Knox C, Tredgett L, Metzakopian E, James LC, McEwan WA. Tuck BJ, et al. Among authors: katsinelos t. Cell Rep. 2022 May 3;39(5):110776. doi: 10.1016/j.celrep.2022.110776. Cell Rep. 2022. PMID: 35508140 Free PMC article.
35 results