Taylor S - Search Results

1

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

Heraud-Farlow JE, Chalk AM, Linder SE, Li Q, Taylor S, White JM, Pang L, Liddicoat BJ, Gupte A, Li JB, Walkley CR. Heraud-Farlow JE, et al. Among authors: taylor s. Genome Biol. 2017 Sep 5;18(1):166. doi: 10.1186/s13059-017-1301-4. Genome Biol. 2017. PMID: 28874170 Free PMC article.

2

Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma.

Baker EK, Taylor S, Gupte A, Chalk AM, Bhattacharya S, Green AC, Martin TJ, Strbenac D, Robinson MD, Purton LE, Walkley CR. Baker EK, et al. Among authors: taylor s. Bone. 2015 Apr;73:223-32. doi: 10.1016/j.bone.2014.12.063. Epub 2015 Jan 5. Bone. 2015. PMID: 25571841 Free article.

3

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: taylor s. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.

4

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.

Baker EK, Taylor S, Gupte A, Sharp PP, Walia M, Walsh NC, Zannettino AC, Chalk AM, Burns CJ, Walkley CR. Baker EK, et al. Among authors: taylor s. Sci Rep. 2015 May 6;5:10120. doi: 10.1038/srep10120. Sci Rep. 2015. PMID: 25944566 Free PMC article.

5

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

Walia MK, Ho PM, Taylor S, Ng AJ, Gupte A, Chalk AM, Zannettino AC, Martin TJ, Walkley CR. Walia MK, et al. Among authors: taylor s. Elife. 2016 Apr 12;5:e13446. doi: 10.7554/eLife.13446. Elife. 2016. PMID: 27070462 Free PMC article.

6

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.

Shekhar TM, Miles MA, Gupte A, Taylor S, Tascone B, Walkley CR, Hawkins CJ. Shekhar TM, et al. Among authors: taylor s. Oncotarget. 2016 Jun 7;7(23):33866-86. doi: 10.18632/oncotarget.8980. Oncotarget. 2016. PMID: 27129149 Free PMC article.

7

Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors.

Sharp PP, Garnier JM, Hatfaludi T, Xu Z, Segal D, Jarman KE, Jousset H, Garnham A, Feutrill JT, Cuzzupe A, Hall P, Taylor S, Walkley CR, Tyler D, Dawson MA, Czabotar P, Wilks AF, Glaser S, Huang DCS, Burns CJ. Sharp PP, et al. Among authors: taylor s. ACS Med Chem Lett. 2017 Nov 14;8(12):1298-1303. doi: 10.1021/acsmedchemlett.7b00389. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259751 Free PMC article.

8

Srsf2^P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells.

Smeets MF, Tan SY, Xu JJ, Anande G, Unnikrishnan A, Chalk AM, Taylor SR, Pimanda JE, Wall M, Purton LE, Walkley CR. Smeets MF, et al. Blood. 2018 Aug 9;132(6):608-621. doi: 10.1182/blood-2018-04-845602. Epub 2018 Jun 14. Blood. 2018. PMID: 29903888 Free article.

9

Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53.

Walia MK, Taylor S, Ho PWM, Martin TJ, Walkley CR. Walia MK, et al. Among authors: taylor s. Cell Death Dis. 2018 Aug 28;9(9):844. doi: 10.1038/s41419-018-0944-8. Cell Death Dis. 2018. PMID: 30154459 Free PMC article.

10

The majority of A-to-I RNA editing is not required for mammalian homeostasis.

Chalk AM, Taylor S, Heraud-Farlow JE, Walkley CR. Chalk AM, et al. Among authors: taylor s. Genome Biol. 2019 Dec 9;20(1):268. doi: 10.1186/s13059-019-1873-2. Genome Biol. 2019. PMID: 31815657 Free PMC article.

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