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Page 1
Showing results for epitope f
Search for Temitope F instead (2 results)
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection(1). ...Here we report a distinct class of broadly neutralizing antibodies that target a d …
Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near univ …
The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Götzke H, Kilisch M, Martínez-Carranza M, Sograte-Idrissi S, Rajavel A, Schlichthaerle T, Engels N, Jungmann R, Stenmark P, Opazo F, Frey S. Götzke H, et al. Nat Commun. 2019 Sep 27;10(1):4403. doi: 10.1038/s41467-019-12301-7. Nat Commun. 2019. PMID: 31562305 Free PMC article.
Specialized epitope tags are widely used for detecting, manipulating or purifying proteins, but often their versatility is limited. Here, we introduce the ALFA-tag, a rationally designed epitope tag that serves a remarkably broad spectrum of applications in life sci …
Specialized epitope tags are widely used for detecting, manipulating or purifying proteins, but often their versatility is limited. H …
The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy.
Claus C, Ferrara-Koller C, Klein C. Claus C, et al. MAbs. 2023 Jan-Dec;15(1):2167189. doi: 10.1080/19420862.2023.2167189. MAbs. 2023. PMID: 36727218 Free PMC article. Review.
The two antibodies display differences in the affinity and the 4-1BB receptor epitope recognition, as well as the isotype, which determines the Fc-gamma-receptor (FcgammaR) crosslinking activity. ...
The two antibodies display differences in the affinity and the 4-1BB receptor epitope recognition, as well as the isotype, which dete …
Homology modeling and epitope prediction of Der f 33.
Teng F, Sun J, Yu L, Li Q, Cui Y. Teng F, et al. Braz J Med Biol Res. 2018 Mar 15;51(5):e6213. doi: 10.1590/1414-431X20186213. Braz J Med Biol Res. 2018. PMID: 29561952 Free PMC article.
A recently identified allergen belonging to the alpha-tubulin protein family, Der f 33, has not been characterized in detail. In this study, we used bioinformatics tools to construct the secondary and tertiary structures and predict the B and T cell epitopes of Der …
A recently identified allergen belonging to the alpha-tubulin protein family, Der f 33, has not been characterized in detail. In this …
Crystal structure and epitope analysis of house dust mite allergen Der f 21.
Pang SL, Ho KL, Waterman J, Rambo RP, Teh AH, Mathavan I, Harris G, Beis K, Say YH, Anusha MS, Sio YY, Chew FT, Ng CL. Pang SL, et al. Sci Rep. 2019 Mar 20;9(1):4933. doi: 10.1038/s41598-019-40879-x. Sci Rep. 2019. PMID: 30894561 Free PMC article.
To reveal the biological function of group 21 allergens and to understand better the allergenicity of the rDer f 21 allergen, we determined the 1.5 A crystal structure of rDer f 21 allergen from Dermatophagoides farinae. ...Six residues, K10, K26, K42, E43, K46, and …
To reveal the biological function of group 21 allergens and to understand better the allergenicity of the rDer f 21 allergen, we dete …
IgE binding activities and in silico epitope prediction of Der f 32 in Dermatophagoides farinae.
Li Y, Wang Y, Ran P, Yang P, Liu Z. Li Y, et al. Immunol Lett. 2019 Sep;213:46-54. doi: 10.1016/j.imlet.2019.07.006. Epub 2019 Aug 2. Immunol Lett. 2019. PMID: 31381937
The B-cell epitopes were distributed completely on the surface of Der f 32 and were located largely in random coils of secondary structures. Hydrophobic and charged amino acids comprised more than 80% of the residues of B-cell epitopes and may participate in …
The B-cell epitopes were distributed completely on the surface of Der f 32 and were located largely in random coils of seconda …
Critical review of conformational B-cell epitope prediction methods.
Cia G, Pucci F, Rooman M. Cia G, et al. Brief Bioinform. 2023 Jan 19;24(1):bbac567. doi: 10.1093/bib/bbac567. Brief Bioinform. 2023. PMID: 36611255 Review.
Accurate in silico prediction of conformational B-cell epitopes would lead to major improvements in disease diagnostics, drug design and vaccine development. ...Here, we rigorously benchmarked nine state-of-the-art conformational B-cell epitope prediction webservers …
Accurate in silico prediction of conformational B-cell epitopes would lead to major improvements in disease diagnostics, drug design …
Identification of a F.VIII epitope recognized by a human hemophilic inhibitor.
Lubahn BC, Ware J, Stafford DW, Reisner HM. Lubahn BC, et al. Blood. 1989 Feb;73(2):497-9. Blood. 1989. PMID: 2465036 Free article.
One epitope has been mapped to the 25-amino acid sequence lys-338 through asp-362 of F.VIII (E338-362). Immunoaffinity-purified antibodies that react with this epitope neutralize F.VIII:C activity. E338-362 is adjacent to an enzymatic cleavage site at …
One epitope has been mapped to the 25-amino acid sequence lys-338 through asp-362 of F.VIII (E338-362). Immunoaffinity-purifie …
A new Karyopherin-beta2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Gonzalez A, Kim HJ, Freibaum BD, Fung HYJ, Brautigam CA, Taylor JP, Chook YM. Gonzalez A, et al. Structure. 2023 Aug 3;31(8):924-934.e4. doi: 10.1016/j.str.2023.05.010. Epub 2023 Jun 5. Structure. 2023. PMID: 37279758
HNRNPH2 (206)RPGPY(210) is a typical R-X(2-4)-P-Y motif comprising PY-NLS epitopes 2 and 3, followed by an additional Karyopherin-beta2-binding epitope, we term epitope 4, at residues (211)DRP(213); no density is present for PY-NLS epitope 1. ...Epi …
HNRNPH2 (206)RPGPY(210) is a typical R-X(2-4)-P-Y motif comprising PY-NLS epitopes 2 and 3, followed by an additional Karyopherin-bet …
Epitope diversity of F strain Mycoplasma gallisepticum detected by flow cytometry.
Brown JE, Branton SL, May JD. Brown JE, et al. Avian Dis. 1997 Apr-Jun;41(2):289-95. Avian Dis. 1997. PMID: 9201390
A culture of F strain Mycoplasma gallisepticum (F-MG) that exhibited an epitope identified by monoclonal antibody (MAb) 6F10 was used to inoculate leghorn hens in two different trials. ...These results suggest that the microenvironment of the colonization sit …
A culture of F strain Mycoplasma gallisepticum (F-MG) that exhibited an epitope identified by monoclonal antibody (MAb) …
6,189 results