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Year | Number of Results |
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2018 | 2 |
2020 | 2 |
2023 | 1 |
2024 | 0 |
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Page 1
Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?
SLAS Discov. 2018 Dec;23(10):991-1017. doi: 10.1177/2472555218786210. Epub 2018 Jul 3.
SLAS Discov. 2018.
PMID: 29969573
Free article.
Review.
Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium.
Seoane PI, Beswick JA, Leach AG, Swanton T, Morris LV, Couper K, Lowe M, Freeman S, Brough D.
Seoane PI, et al. Among authors: swanton t.
Cell Death Discov. 2023 Dec 22;9(1):469. doi: 10.1038/s41420-023-01756-9.
Cell Death Discov. 2023.
PMID: 38129373
Free PMC article.
Item in Clipboard
Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome.
Baldwin AG, Tapia VS, Swanton T, White CS, Beswick JA, Brough D, Freeman S.
Baldwin AG, et al. Among authors: swanton t.
ChemMedChem. 2018 Feb 20;13(4):312-320. doi: 10.1002/cmdc.201700731. Epub 2018 Feb 5.
ChemMedChem. 2018.
PMID: 29331080
Free PMC article.
Item in Clipboard
LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation.
Green JP, Swanton T, Morris LV, El-Sharkawy LY, Cook J, Yu S, Beswick J, Adamson AD, Humphreys NE, Bryce R, Freeman S, Lawrence C, Brough D.
Green JP, et al. Among authors: swanton t.
Elife. 2020 Nov 20;9:e59704. doi: 10.7554/eLife.59704.
Elife. 2020.
PMID: 33216713
Free PMC article.
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Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl- channel modulation.
Swanton T, Beswick JA, Hammadi H, Morris L, Williams D, de Cesco S, El-Sharkawy L, Yu S, Green J, Davis JB, Lawrence CB, Brough D, Freeman S.
Swanton T, et al.
Chem Sci. 2020 Oct 12;11(43):11720-11728. doi: 10.1039/d0sc03828h.
Chem Sci. 2020.
PMID: 34094411
Free PMC article.
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