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A knockin mouse model of the Bardet-Biedl syndrome 1 M390R mutation has cilia defects, ventriculomegaly, retinopathy, and obesity.
Davis RE, Swiderski RE, Rahmouni K, Nishimura DY, Mullins RF, Agassandian K, Philp AR, Searby CC, Andrews MP, Thompson S, Berry CJ, Thedens DR, Yang B, Weiss RM, Cassell MD, Stone EM, Sheffield VC. Davis RE, et al. Among authors: thedens dr. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19422-7. doi: 10.1073/pnas.0708571104. Epub 2007 Nov 21. Proc Natl Acad Sci U S A. 2007. PMID: 18032602 Free PMC article.
Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation.
Lobas MA, Helsper L, Vernon CG, Schreiner D, Zhang Y, Holtzman MJ, Thedens DR, Weiner JA. Lobas MA, et al. Among authors: thedens dr. J Neurochem. 2012 Mar;120(6):913-27. doi: 10.1111/j.1471-4159.2011.07587.x. Epub 2011 Dec 7. J Neurochem. 2012. PMID: 22092001 Free PMC article.
FoxO6 regulates Hippo signaling and growth of the craniofacial complex.
Sun Z, da Fontoura CSG, Moreno M, Holton NE, Sweat M, Sweat Y, Lee MK, Arbon J, Bidlack FB, Thedens DR, Nopoulos P, Cao H, Eliason S, Weinberg SM, Martin JF, Moreno-Uribe L, Amendt BA. Sun Z, et al. Among authors: thedens dr. PLoS Genet. 2018 Oct 4;14(10):e1007675. doi: 10.1371/journal.pgen.1007675. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30286078 Free PMC article.
Detecting activity-evoked pH changes in human brain.
Magnotta VA, Heo HY, Dlouhy BJ, Dahdaleh NS, Follmer RL, Thedens DR, Welsh MJ, Wemmie JA. Magnotta VA, et al. Among authors: thedens dr. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8270-3. doi: 10.1073/pnas.1205902109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566645 Free PMC article. Clinical Trial.
Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
Carter CS, Vogel TW, Zhang Q, Seo S, Swiderski RE, Moninger TO, Cassell MD, Thedens DR, Keppler-Noreuil KM, Nopoulos P, Nishimura DY, Searby CC, Bugge K, Sheffield VC. Carter CS, et al. Among authors: thedens dr. Nat Med. 2012 Dec;18(12):1797-804. doi: 10.1038/nm.2996. Epub 2012 Nov 18. Nat Med. 2012. PMID: 23160237 Free PMC article.
61 results