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Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.
Tokarsky EJ, Crow JC, Guenther LM, Sherman J, Taslim C, Alexe G, Pishas KI, Rask G, Justis BS, Kasumova A, Stegmaier K, Lessnick SL, Theisen ER. Tokarsky EJ, et al. Among authors: theisen er. Mol Cancer Res. 2022 Jul 6;20(7):1035-1046. doi: 10.1158/1541-7786.MCR-22-0027. Mol Cancer Res. 2022. PMID: 35298000 Free PMC article.
Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.
Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL. Pishas KI, et al. Among authors: theisen er. Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11. Mol Cancer Ther. 2018. PMID: 29997151 Free PMC article.
Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma.
Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL. Patel PO, et al. Among authors: theisen er. Oncotarget. 2019 Jun 11;10(39):3865-3878. doi: 10.18632/oncotarget.26988. eCollection 2019 Jun 11. Oncotarget. 2019. PMID: 31231465 Free PMC article.
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.
Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL. Boone MA, et al. Among authors: theisen er. Oncogene. 2021 Jul;40(29):4759-4769. doi: 10.1038/s41388-021-01876-5. Epub 2021 Jun 18. Oncogene. 2021. PMID: 34145397 Free PMC article.
16 results