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Page 1
Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Cancer Cell. 2020 Dec 14;38(6):872-890.e6. doi: 10.1016/j.ccell.2020.10.010. Epub 2020 Nov 19.
Cancer Cell. 2020.
PMID: 33217342
Free PMC article.
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.
Lin S, Larrue C, Scheidegger NK, Seong BKA, Dharia NV, Kuljanin M, Wechsler CS, Kugener G, Robichaud AL, Conway AS, Mashaka T, Mouche S, Adane B, Ryan JA, Mancias JD, Younger ST, Piccioni F, Lee LH, Wunderlich M, Letai A, Tamburini J, Stegmaier K.
Lin S, et al. Among authors: mashaka t.
Cancer Discov. 2022 Feb;12(2):432-449. doi: 10.1158/2159-8290.CD-20-1851. Epub 2021 Sep 16.
Cancer Discov. 2022.
PMID: 34531254
Free PMC article.
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BH3 profiling discriminates on-target small molecule BH3 mimetics from putative mimetics.
Villalobos-Ortiz M, Ryan J, Mashaka TN, Opferman JT, Letai A.
Villalobos-Ortiz M, et al. Among authors: mashaka tn.
Cell Death Differ. 2020 Mar;27(3):999-1007. doi: 10.1038/s41418-019-0391-9. Epub 2019 Jul 22.
Cell Death Differ. 2020.
PMID: 31332296
Free PMC article.
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Adding venetoclax to fludarabine/busulfan RIC transplant for high-risk MDS and AML is feasible, safe, and active.
Garcia JS, Kim HT, Murdock HM, Cutler CS, Brock J, Gooptu M, Ho VT, Koreth J, Nikiforow S, Romee R, Shapiro R, Loschi F, Ryan J, Fell G, Karp HQ, Lucas F, Kim AS, Potter D, Mashaka T, Stone RM, DeAngelo DJ, Letai A, Lindsley RC, Soiffer RJ, Antin JH.
Garcia JS, et al. Among authors: mashaka t.
Blood Adv. 2021 Dec 28;5(24):5536-5545. doi: 10.1182/bloodadvances.2021005566.
Blood Adv. 2021.
PMID: 34614506
Free PMC article.
Clinical Trial.
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