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FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M. Doll S, et al. Among authors: vignane t. Nature. 2019 Nov;575(7784):693-698. doi: 10.1038/s41586-019-1707-0. Epub 2019 Oct 21. Nature. 2019. PMID: 31634899
Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.
Giovinazzo D, Bursac B, Sbodio JI, Nalluru S, Vignane T, Snowman AM, Albacarys LM, Sedlak TW, Torregrossa R, Whiteman M, Filipovic MR, Snyder SH, Paul BD. Giovinazzo D, et al. Among authors: vignane t. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017225118. doi: 10.1073/pnas.2017225118. Proc Natl Acad Sci U S A. 2021. PMID: 33431651 Free PMC article.
Emerging Chemical Biology of Protein Persulfidation.
Vignane T, Filipovic MR. Vignane T, et al. Antioxid Redox Signal. 2023 Jul;39(1-3):19-39. doi: 10.1089/ars.2023.0352. Epub 2023 Jul 10. Antioxid Redox Signal. 2023. PMID: 37288744 Free PMC article. Review.
Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78.
Peng YJ, Nanduri J, Wang N, Kumar GK, Bindokas V, Paul BD, Chen X, Fox AP, Vignane T, Filipovic MR, Prabhakar NR. Peng YJ, et al. Among authors: vignane t. Sci Adv. 2023 Jul 7;9(27):eadf3026. doi: 10.1126/sciadv.adf3026. Epub 2023 Jul 5. Sci Adv. 2023. PMID: 37406126 Free PMC article.
The Role of Protein Persulfidation in Brain Aging and Neurodegeneration.
Petrovic D, Kouroussis E, Vignane T, Filipovic MR. Petrovic D, et al. Among authors: vignane t. Front Aging Neurosci. 2021 Jun 23;13:674135. doi: 10.3389/fnagi.2021.674135. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34248604 Free PMC article. Review.
Zinc complexes of chloroquine and hydroxychloroquine versus the mixtures of their components: Structures, solution equilibria/speciation and cellular zinc uptake.
Squarcina A, Franke A, Senft L, Onderka C, Langer J, Vignane T, Filipovic MR, Grill P, Michalke B, Ivanović-Burmazović I. Squarcina A, et al. Among authors: vignane t. J Inorg Biochem. 2024 Mar;252:112478. doi: 10.1016/j.jinorgbio.2024.112478. Epub 2024 Jan 3. J Inorg Biochem. 2024. PMID: 38218140 Free article.