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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Martinelli S, Anderzhanova EA, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, Heinz DE, Ebert T, Hartmann J, Geiger TM, Döngi M, Hafner K, Pöhlmann ML, Jollans L, Philipsen A, Schmidt SV, Schmidt U, Maccarrone G, Stein V, Hausch F, Turck CW, Schmidt MV, Gellner AK, Kuster B, Gassen NC. Martinelli S, et al. Among authors: bajaj t. Nat Commun. 2021 Jul 30;12(1):4643. doi: 10.1038/s41467-021-24810-5. Nat Commun. 2021. PMID: 34330919 Free PMC article.
Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5.
Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, Gassen NC, Schmidt MV, Ressler KJ. Hartmann J, et al. Among authors: bajaj t. Cell Rep. 2021 Jun 1;35(9):109185. doi: 10.1016/j.celrep.2021.109185. Cell Rep. 2021. PMID: 34077736 Free PMC article.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Ebert T, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Trussell DT, Li KX, Pöhlmann ML, Mackert S, Geiger TM, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA Jr, Hausch F, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. Among authors: bajaj t. Nat Commun. 2024 Mar 25;15(1):2635. doi: 10.1038/s41467-024-46953-x. Nat Commun. 2024. PMID: 38528004 Free PMC article.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Li K, Pöhlmann ML, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. Among authors: bajaj t. bioRxiv [Preprint]. 2023 Apr 3:2023.04.03.534570. doi: 10.1101/2023.04.03.534570. bioRxiv. 2023. PMID: 37066393 Free PMC article. Updated. Preprint.
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning.
Stepan J, Heinz DE, Dethloff F, Bajaj T, Zellner A, Hafner K, Wiechmann S, Mackert S, Mecdad Y, Rabenstein M, Ebert T, Martinelli S, Häusl AS, Pöhlmann ML, Hermann A, Ma X, Pavenstädt H, Schmidt MV, Philipsen A, Turck CW, Deussing JM, Kuster B, Wehr MC, Stein V, Kremerskothen J, Wotjak CT, Gassen NC. Stepan J, et al. Among authors: bajaj t. Cell Rep. 2022 Dec 6;41(10):111766. doi: 10.1016/j.celrep.2022.111766. Cell Rep. 2022. PMID: 36476872 Free article.
Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ; Traumatic Stress Brain Research Group; PTSD BrainOmics Project of the PsychENCODE Consortium; PTSD Working Group of the Psychiatric Genomics Consortium; Carlezon WA Jr, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Chatzinakos C, et al. Among authors: bajaj t. Am J Psychiatry. 2023 Oct 1;180(10):739-754. doi: 10.1176/appi.ajp.20220478. Epub 2023 Jul 26. Am J Psychiatry. 2023. PMID: 37491937
16 results