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Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone-receptor activation.
Chen YS, Gleaton J, Yang Y, Dhayalan B, Phillips NB, Liu Y, Broadwater L, Jarosinski MA, Chatterjee D, Lawrence MC, Hattier T, Michael MD, Weiss MA. Chen YS, et al. Among authors: hattier t. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2103518118. doi: 10.1073/pnas.2103518118. Proc Natl Acad Sci U S A. 2021. PMID: 34290145 Free PMC article.
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron.
Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Honda K, et al. Among authors: hattier t. J Biol Chem. 2005 Jun 3;280(22):20978-86. doi: 10.1074/jbc.M500526200. Epub 2005 Mar 14. J Biol Chem. 2005. PMID: 15767256 Free article.