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Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression.
Thompson AGB, Luk C, Heslegrave AJ, Zetterberg H, Mead SH, Collinge J, Jackson GS. Thompson AGB, et al. J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):955-961. doi: 10.1136/jnnp-2017-317793. Epub 2018 Feb 27. J Neurol Neurosurg Psychiatry. 2018. PMID: 29487167 Free PMC article.
The cognitive profile of prion disease: a prospective clinical and imaging study.
Caine D, Tinelli RJ, Hyare H, De Vita E, Lowe J, Lukic A, Thompson A, Porter MC, Cipolotti L, Rudge P, Collinge J, Mead S. Caine D, et al. Among authors: thompson a. Ann Clin Transl Neurol. 2015 May;2(5):548-58. doi: 10.1002/acn3.195. Epub 2015 Apr 7. Ann Clin Transl Neurol. 2015. PMID: 26000326 Free PMC article.
Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease.
Mead S, Burnell M, Lowe J, Thompson A, Lukic A, Porter MC, Carswell C, Kaski D, Kenny J, Mok TH, Bjurstrom N, Franko E, Gorham M, Druyeh R, Wadsworth JD, Jaunmuktane Z, Brandner S, Hyare H, Rudge P, Walker AS, Collinge J. Mead S, et al. Among authors: thompson a. JAMA Neurol. 2016 Apr;73(4):447-55. doi: 10.1001/jamaneurol.2015.4885. JAMA Neurol. 2016. PMID: 26902324 Free PMC article.
Quantitative EEG parameters correlate with the progression of human prion diseases.
Franko E, Wehner T, Joly O, Lowe J, Porter MC, Kenny J, Thompson A, Rudge P, Collinge J, Mead S. Franko E, et al. Among authors: thompson a. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1061-7. doi: 10.1136/jnnp-2016-313501. Epub 2016 Jul 13. J Neurol Neurosurg Psychiatry. 2016. PMID: 27413165 Free PMC article. Review.
Predictive testing for inherited prion disease: report of 22 years experience.
Owen J, Beck J, Campbell T, Adamson G, Gorham M, Thompson A, Smithson S, Rosser E, Rudge P, Collinge J, Mead S. Owen J, et al. Among authors: thompson a. Eur J Hum Genet. 2014 Dec;22(12):1351-6. doi: 10.1038/ejhg.2014.42. Epub 2014 Apr 9. Eur J Hum Genet. 2014. PMID: 24713662 Free PMC article.
Putaminal diffusion tensor imaging measures predict disease severity across human prion diseases.
Hyare H, De Vita E, Porter MC, Simpson I, Ridgway G, Lowe J, Thompson A, Carswell C, Ourselin S, Modat M, Dos Santos Canas L, Caine D, Fox Z, Rudge P, Collinge J, Mead S, Thornton JS. Hyare H, et al. Among authors: thompson a. Brain Commun. 2020 Apr 8;2(1):fcaa032. doi: 10.1093/braincomms/fcaa032. eCollection 2020. Brain Commun. 2020. PMID: 32954290 Free PMC article.
Behavioral and psychiatric symptoms in prion disease.
Thompson A, MacKay A, Rudge P, Lukic A, Porter MC, Lowe J, Collinge J, Mead S. Thompson A, et al. Am J Psychiatry. 2014 Mar;171(3):265-74. doi: 10.1176/appi.ajp.2013.12111460. Am J Psychiatry. 2014. PMID: 24585329 Review.
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