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Can we discover pharmacological promiscuity early in the drug discovery process?
Drug Discov Today. 2012 Apr;17(7-8):325-35. doi: 10.1016/j.drudis.2012.01.001. Epub 2012 Jan 16.
Drug Discov Today. 2012.
PMID: 22269136
Review.
Safety screening in early drug discovery: An optimized assay panel.
Bendels S, Bissantz C, Fasching B, Gerebtzoff G, Guba W, Kansy M, Migeon J, Mohr S, Peters JU, Tillier F, Wyler R, Lerner C, Kramer C, Richter H, Roberts S.
Bendels S, et al. Among authors: tillier f.
J Pharmacol Toxicol Methods. 2019 Sep-Oct;99:106609. doi: 10.1016/j.vascn.2019.106609. Epub 2019 Jul 5.
J Pharmacol Toxicol Methods. 2019.
PMID: 31284073
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BioPrint meets the AI age: development of artificial intelligence-based ADMET models for the drug-discovery platform SAFIRE.
Biehn SE, Goncalves LM, Lehmann J, Marty JD, Mueller C, Ramirez SA, Tillier F, Sage CR.
Biehn SE, et al. Among authors: tillier f.
Future Med Chem. 2024 Apr;16(7):587-599. doi: 10.4155/fmc-2024-0007. Epub 2024 Feb 19.
Future Med Chem. 2024.
PMID: 38372202
Free article.
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Bovine papillomavirus type 1 DNA replication: the transcriptional activator E2 acts in vitro as a specificity factor.
Bonne-Andréa C, Tillier F, McShan GD, Wilson VG, Clertant P.
Bonne-Andréa C, et al. Among authors: tillier f.
J Virol. 1997 Sep;71(9):6805-15. doi: 10.1128/JVI.71.9.6805-6815.1997.
J Virol. 1997.
PMID: 9261405
Free PMC article.
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Bovine papillomavirus E1 protein binds specifically DNA polymerase alpha but not replication protein A.
Bonne-Andrea C, Santucci S, Clertant P, Tillier F.
Bonne-Andrea C, et al. Among authors: tillier f.
J Virol. 1995 Apr;69(4):2341-50. doi: 10.1128/JVI.69.4.2341-2350.1995.
J Virol. 1995.
PMID: 7884880
Free PMC article.
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Tumorigenic transformation of rat FR3T3 fibroblasts carrying an activated myc oncogene requires subsequent mutational events.
Mougneau E, Cerni C, Tillier F, Cuzin F.
Mougneau E, et al. Among authors: tillier f.
Oncogene Res. 1988;2(2):177-88.
Oncogene Res. 1988.
PMID: 3217111
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Catabolite modulator factor: physiological properties and in vivo effects.
Dessein A, Tillier F, Ullmann A.
Dessein A, et al. Among authors: tillier f.
Mol Gen Genet. 1978 Jun 1;162(1):89-94. doi: 10.1007/BF00333854.
Mol Gen Genet. 1978.
PMID: 209310
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Catabolite modulator factor: a possible mediator of catabolite repression in bacteria.
Ullmann A, Tillier F, Monod J.
Ullmann A, et al. Among authors: tillier f.
Proc Natl Acad Sci U S A. 1976 Oct;73(10):3476-9. doi: 10.1073/pnas.73.10.3476.
Proc Natl Acad Sci U S A. 1976.
PMID: 185615
Free PMC article.
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