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Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.
Toledo MAS, Gatz M, Sontag S, Gleixner KV, Eisenwort G, Feldberg K, Hamouda AEI, Kluge F, Guareschi R, Rossetti G, Sechi AS, Dufva OMJ, Mustjoki SM, Maurer A, Schüler HM, Goetzke R, Braunschweig T, Kaiser A, Panse J, Jawhar M, Reiter A, Hilberg F, Ettmayer P, Wagner W, Koschmieder S, Brümmendorf TH, Valent P, Chatain N, Zenke M. Toledo MAS, et al. Blood. 2021 Apr 15;137(15):2070-2084. doi: 10.1182/blood.2019004509. Blood. 2021. PMID: 33512435 Free article.
Human DC3 Antigen Presenting Dendritic Cells From Induced Pluripotent Stem Cells.
Satoh T, Toledo MAS, Boehnke J, Olschok K, Flosdorf N, Götz K, Küstermann C, Sontag S, Seré K, Koschmieder S, Brümmendorf TH, Chatain N, Tagawa YI, Zenke M. Satoh T, et al. Among authors: toledo mas. Front Cell Dev Biol. 2021 Jul 22;9:667304. doi: 10.3389/fcell.2021.667304. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34368123 Free PMC article.
The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates.
Elsafi Mabrouk MH, Goetzke R, Abagnale G, Yesilyurt B, Salz L, Cypris O, Glück P, Liesenfelder S, Zeevaert K, Ma Z, Toledo MAS, Li R, Costa IG, Lampert A, Pachauri V, Schnakenberg U, Zenke M, Wagner W. Elsafi Mabrouk MH, et al. Among authors: toledo mas. Biomaterials. 2022 Mar;282:121389. doi: 10.1016/j.biomaterials.2022.121389. Epub 2022 Jan 25. Biomaterials. 2022. PMID: 35121357 Free article.
Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia.
Atakhanov S, Christen D, Rolles B, Schüler HM, Panse J, Chatain N, Koschmieder S, Brümmendorf TH, Toledo MAS, Zenke M. Atakhanov S, et al. Among authors: toledo mas. Ann Hematol. 2022 Nov;101(11):2533-2536. doi: 10.1007/s00277-022-04975-9. Epub 2022 Sep 20. Ann Hematol. 2022. PMID: 36125543 Free PMC article. No abstract available.
Capitalizing on paradoxical activation of the mitogen-activated protein kinase pathway for treatment of Imatinib-resistant mast cell leukemia.
Wilhelm T, Toledo MAS, Simons I, Stuth C, Mohta V, Mülfarth R, Nitsche M, Maschke-Neuß K, Schmitz S, Kaiser A, Panse J, Christen D, Arock M, Zenke M, Huber M. Wilhelm T, et al. Among authors: toledo mas. Hematol Oncol. 2023 Aug;41(3):520-534. doi: 10.1002/hon.3100. Epub 2022 Nov 30. Hematol Oncol. 2023. PMID: 36383121
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Flosdorf N, Böhnke J, de Toledo MAS, Lutterbach N, Lerma VG, Graßhoff M, Olschok K, Gupta S, Tharmapalan V, Schmitz S, Götz K, Schüler HM, Maurer A, Sontag S, Küstermann C, Seré K, Wagner W, Costa IG, Brümmendorf TH, Koschmieder S, Chatain N, Castilho M, Schneider RK, Zenke M. Flosdorf N, et al. Among authors: de toledo mas. Stem Cell Reports. 2024 Feb 13;19(2):224-238. doi: 10.1016/j.stemcr.2023.12.011. Epub 2024 Jan 25. Stem Cell Reports. 2024. PMID: 38278152 Free PMC article.
41 results