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Autophagy in healthy aging and disease.
Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF. Aman Y, et al. Among authors: schmauck medina t. Nat Aging. 2021 Aug;1(8):634-650. doi: 10.1038/s43587-021-00098-4. Epub 2021 Aug 12. Nat Aging. 2021. PMID: 34901876 Free PMC article. Review.
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary.
Schmauck-Medina T, Molière A, Lautrup S, Zhang J, Chlopicki S, Madsen HB, Cao S, Soendenbroe C, Mansell E, Vestergaard MB, Li Z, Shiloh Y, Opresko PL, Egly JM, Kirkwood T, Verdin E, Bohr VA, Cox LS, Stevnsner T, Rasmussen LJ, Fang EF. Schmauck-Medina T, et al. Aging (Albany NY). 2022 Aug 29;14(16):6829-6839. doi: 10.18632/aging.204248. Epub 2022 Aug 29. Aging (Albany NY). 2022. PMID: 36040386 Free PMC article.
Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.
Xie C, Zhuang XX, Niu Z, Ai R, Lautrup S, Zheng S, Jiang Y, Han R, Gupta TS, Cao S, Lagartos-Donate MJ, Cai CZ, Xie LM, Caponio D, Wang WW, Schmauck-Medina T, Zhang J, Wang HL, Lou G, Xiao X, Zheng W, Palikaras K, Yang G, Caldwell KA, Caldwell GA, Shen HM, Nilsen H, Lu JH, Fang EF. Xie C, et al. Among authors: schmauck medina t. Nat Biomed Eng. 2022 Jan;6(1):76-93. doi: 10.1038/s41551-021-00819-5. Epub 2022 Jan 6. Nat Biomed Eng. 2022. PMID: 34992270 Free PMC article.
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
Lu G, Tan HWS, Schmauck-Medina T, Wang L, Chen J, Cho YL, Chen K, Zhang JZ, He W, Wu Y, Xia D, Zhou J, Fang EF, Fang L, Liu W, Shen HM. Lu G, et al. Among authors: schmauck medina t. Autophagy. 2022 Dec;18(12):2865-2879. doi: 10.1080/15548627.2022.2052461. Epub 2022 Apr 7. Autophagy. 2022. PMID: 35389758 Free PMC article.
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Among authors: schmauck medina t. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies.
Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H, Gonos ES, Scheibye-Knudsen M, Chen G, Kato H, Selbæk G, Fladby T, Nilsson P, Simonsen A, Aarsland D, Lautrup S, Ottersen OP, Cox LS, Fang EF. Wang HL, et al. Among authors: schmauck medina t. J Gerontol A Biol Sci Med Sci. 2024 Apr 1;79(4):glae029. doi: 10.1093/gerona/glae029. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38289789 Free PMC article.