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Page 1
MYCL-mediated reprogramming expands pancreatic insulin-producing cells.
Hirano M, So Y, Tsunekawa S, Kabata M, Ohta S, Sagara H, Sankoda N, Taguchi J, Yamada Y, Ukai T, Kato M, Nakamura J, Ozawa M, Yamamoto T, Yamada Y. Hirano M, et al. Among authors: ukai t. Nat Metab. 2022 Feb;4(2):254-268. doi: 10.1038/s42255-022-00530-y. Epub 2022 Feb 10. Nat Metab. 2022. PMID: 35145326
In vivo reprogramming drives Kras-induced cancer development.
Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y. Shibata H, et al. Among authors: ukai t. Nat Commun. 2018 May 25;9(1):2081. doi: 10.1038/s41467-018-04449-5. Nat Commun. 2018. PMID: 29802314 Free PMC article.
The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Ito K, Nagata K, Ohta S, Matsuda Y, Ukai T, Yasuda I, Ota A, Kobayashi R, Kabata M, Sankoda N, Maeda T, Woltjen K, Yang L, Maruyama R, Katayama R, Yamamoto T, Yamada Y. Ito K, et al. Among authors: ukai t. Cell Rep. 2022 Apr 26;39(4):110721. doi: 10.1016/j.celrep.2022.110721. Cell Rep. 2022. PMID: 35476996 Free article.
Generation of mice for evaluating endogenous p16Ink4a protein expression.
Shimada-Takayama Y, Yasuda T, Ukai T, Taguchi J, Ozawa M, Sankoda N, Ohta S, Yamada Y. Shimada-Takayama Y, et al. Among authors: ukai t. Biochem Biophys Res Commun. 2022 Apr 9;599:43-50. doi: 10.1016/j.bbrc.2022.02.005. Epub 2022 Feb 9. Biochem Biophys Res Commun. 2022. PMID: 35168063
Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas.
Komura S, Ito K, Ohta S, Ukai T, Kabata M, Itakura F, Semi K, Matsuda Y, Hashimoto K, Shibata H, Sone M, Jo N, Sekiguchi K, Ohno T, Akiyama H, Shimizu K, Woltjen K, Ozawa M, Toguchida J, Yamamoto T, Yamada Y. Komura S, et al. Among authors: ukai t. Nat Commun. 2019 Sep 5;10(1):3999. doi: 10.1038/s41467-019-11745-1. Nat Commun. 2019. PMID: 31488818 Free PMC article.
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency.
Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y. Taguchi J, et al. Among authors: ukai t. Nat Commun. 2021 Aug 19;12(1):5041. doi: 10.1038/s41467-021-25249-4. Nat Commun. 2021. PMID: 34413299 Free PMC article.
12 results