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Year Number of Results
2016 1
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2020 12
2021 7
2022 4
2023 6
2024 2

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27 results

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Page 1
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.
Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Dodd A, Liang SB, Borgida A, Chadwick D, Kalimuthu S, Lungu I, Bartlett JMS, Krzyzanowski PM, Sandhu V, Tiriac H, Froeling FEM, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Jones SJM, Marra MA, Laskin J, Chetty R, Stein LD, Zogopoulos G, Haibe-Kains B, Campbell PJ, Tuveson DA, Knox JJ, Fischer SE, Gallinger S, Notta F. Chan-Seng-Yue M, et al. Among authors: topham jt. Nat Genet. 2020 Feb;52(2):231-240. doi: 10.1038/s41588-019-0566-9. Epub 2020 Jan 13. Nat Genet. 2020. PMID: 31932696
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.
Topham JT, Tsang ES, Karasinska JM, Metcalfe A, Ali H, Kalloger SE, Csizmok V, Williamson LM, Titmuss E, Nielsen K, Negri GL, Spencer Miko SE, Jang GH, Denroche RE, Wong HL, O'Kane GM, Moore RA, Mungall AJ, Loree JM, Notta F, Wilson JM, Bathe OF, Tang PA, Goodwin R, Morin GB, Knox JJ, Gallinger S, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Topham JT, et al. Nat Commun. 2022 Oct 8;13(1):5941. doi: 10.1038/s41467-022-33718-7. Nat Commun. 2022. PMID: 36209277 Free PMC article.
Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study.
Huey RW, Shah AT, Reddi HV, Dasari P, Topham JT, Hwang H, Dhillon N, Willett A, Smaglo BG, Estrella JS, Rashid A, Matamoros A, Overman MJ, Choquette L, Omerza G, Kelly K, Wang X, Loree JM, Rueter J, Varadhachary GR, Raghav K. Huey RW, et al. Among authors: topham jt. J Natl Cancer Inst. 2023 Aug 8;115(8):994-997. doi: 10.1093/jnci/djad095. J Natl Cancer Inst. 2023. PMID: 37202363 Clinical Trial.
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration.
Tsang ES, Csizmok V, Williamson LM, Pleasance E, Topham JT, Karasinska JM, Titmuss E, Schrader I, Yip S, Tessier-Cloutier B, Mungall K, Ng T, Sun S, Lim HJ, Loree JM, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Tsang ES, et al. Among authors: topham jt. NPJ Precis Oncol. 2023 Mar 24;7(1):31. doi: 10.1038/s41698-023-00368-x. NPJ Precis Oncol. 2023. PMID: 36964191 Free PMC article.
The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.
Renouf DJ, Loree JM, Knox JJ, Topham JT, Kavan P, Jonker D, Welch S, Couture F, Lemay F, Tehfe M, Harb M, Aucoin N, Ko YJ, Tang PA, Ramjeesingh R, Meyers BM, Kim CA, Du P, Jia S, Schaeffer DF, Gill S, Tu D, O'Callaghan CJ. Renouf DJ, et al. Among authors: topham jt. Nat Commun. 2022 Aug 26;13(1):5020. doi: 10.1038/s41467-022-32591-8. Nat Commun. 2022. PMID: 36028483 Free PMC article. Clinical Trial.
The Neoantigen Landscape of the Coding and Noncoding Cancer Genome Space.
Lau TTY, Sefid Dashti ZJ, Titmuss E, Pender A, Topham JT, Bridgers J, Loree JM, Feng X, Pleasance ED, Renouf DJ, Schrader KA, Sun S, Ho C, Marra MA, Laskin J, Karsan A. Lau TTY, et al. Among authors: topham jt. J Mol Diagn. 2022 Jun;24(6):609-618. doi: 10.1016/j.jmoldx.2022.02.004. Epub 2022 Mar 31. J Mol Diagn. 2022. PMID: 35367630 Free article.
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.
Grant RC, Denroche R, Jang GH, Nowak KM, Zhang A, Borgida A, Holter S, Topham JT, Wilson J, Dodd A, Jang R, Prince R, Karasinska JM, Schaeffer DF, Wang Y, Zogopoulos G, Berry S, Simeone D, Renouf DJ, Notta F, O'Kane G, Knox J, Fischer S, Gallinger S. Grant RC, et al. Among authors: topham jt. Gut. 2021 Oct;70(10):1894-1903. doi: 10.1136/gutjnl-2020-320730. Epub 2020 Sep 15. Gut. 2021. PMID: 32933947
27 results