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Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.
Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Marabelle A, et al. Among authors: torchia j. J Clin Invest. 2013 Jun;123(6):2447-63. doi: 10.1172/JCI64859. J Clin Invest. 2013. PMID: 23728179 Free PMC article.
Emerging concepts in PD-1 checkpoint biology.
Pauken KE, Torchia JA, Chaudhri A, Sharpe AH, Freeman GJ. Pauken KE, et al. Among authors: torchia ja. Semin Immunol. 2021 Feb;52:101480. doi: 10.1016/j.smim.2021.101480. Epub 2021 May 15. Semin Immunol. 2021. PMID: 34006473 Free PMC article. Review.
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy.
Chaudhri A, Bu X, Wang Y, Gomez M, Torchia JA, Hua P, Hung SH, Davies MA, Lizee GA, von Andrian U, Hwu P, Freeman GJ. Chaudhri A, et al. Among authors: torchia ja. Front Immunol. 2023 Sep 13;14:1237715. doi: 10.3389/fimmu.2023.1237715. eCollection 2023. Front Immunol. 2023. PMID: 37771579 Free PMC article.
87 results