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UBTD1 is a mechano-regulator controlling cancer aggressiveness.
Torrino S, Roustan FR, Kaminski L, Bertero T, Pisano S, Ambrosetti D, Dufies M, Uhler JP, Lemichez E, Mettouchi A, Gesson M, Laurent K, Gaggioli C, Michiels JF, Lamaze C, Bost F, Clavel S. Torrino S, et al. EMBO Rep. 2019 Apr;20(4):e46570. doi: 10.15252/embr.201846570. Epub 2019 Feb 25. EMBO Rep. 2019. PMID: 30804013 Free PMC article.
Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension.
Negi V, Yang J, Speyer G, Pulgarin A, Handen A, Zhao J, Tai YY, Tang Y, Culley MK, Yu Q, Forsythe P, Gorelova A, Watson AM, Al Aaraj Y, Satoh T, Sharifi-Sanjani M, Rajaratnam A, Sembrat J, Provencher S, Yin X, Vargas SO, Rojas M, Bonnet S, Torrino S, Wagner BK, Schreiber SL, Dai M, Bertero T, Al Ghouleh I, Kim S, Chan SY. Negi V, et al. Among authors: torrino s. Sci Adv. 2021 Oct 22;7(43):eabh3794. doi: 10.1126/sciadv.abh3794. Epub 2021 Oct 20. Sci Adv. 2021. PMID: 34669463 Free PMC article.
EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription.
Torrino S, Shen WW, Blouin CM, Mani SK, Viaris de Lesegno C, Bost P, Grassart A, Köster D, Valades-Cruz CA, Chambon V, Johannes L, Pierobon P, Soumelis V, Coirault C, Vassilopoulos S, Lamaze C. Torrino S, et al. J Cell Biol. 2018 Dec 3;217(12):4092-4105. doi: 10.1083/jcb.201801122. Epub 2018 Oct 22. J Cell Biol. 2018. PMID: 30348749 Free PMC article.
[Caveolae mechanotranduction: a new role for the EHD2 ATPase].
Lamaze C, Torrino S. Lamaze C, et al. Among authors: torrino s. Med Sci (Paris). 2020 Mar;36(3):209-212. doi: 10.1051/medsci/2020033. Epub 2020 Mar 31. Med Sci (Paris). 2020. PMID: 32228835 Free article. French. No abstract available.
Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma.
Dufies M, Verbiest A, Cooley LS, Ndiaye PD, He X, Nottet N, Souleyreau W, Hagege A, Torrino S, Parola J, Giuliano S, Borchiellini D, Schiappa R, Mograbi B, Zucman-Rossi J, Bensalah K, Ravaud A, Auberger P, Bikfalvi A, Chamorey E, Rioux-Leclercq N, Mazure NM, Beuselinck B, Cao Y, Bernhard JC, Ambrosetti D, Pagès G. Dufies M, et al. Among authors: torrino s. Commun Biol. 2021 Feb 5;4(1):166. doi: 10.1038/s42003-021-01653-w. Commun Biol. 2021. PMID: 33547392 Free PMC article.
PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness.
Kaminski L, Torrino S, Dufies M, Djabari Z, Haider R, Roustan FR, Jaune E, Laurent K, Nottet N, Michiels JF, Gesson M, Rocchi S, Mazure NM, Durand M, Tanti JF, Ambrosetti D, Clavel S, Ben-Sahra I, Bost F. Kaminski L, et al. Among authors: torrino s. Cancer Res. 2019 Jul 1;79(13):3268-3280. doi: 10.1158/0008-5472.CAN-18-2043. Epub 2019 May 7. Cancer Res. 2019. PMID: 31064849 Free PMC article.
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