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Year Number of Results
2020 1
2022 1
2023 10
2024 3

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15 results

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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.
Zhou W, Liu H, Yuan Z, Zundell J, Towers M, Lin J, Lombardi S, Nie H, Murphy B, Yang T, Wang C, Liao L, Goldman AR, Kannan T, Kossenkov AV, Drapkin R, Montaner LJ, Claiborne DT, Zhang N, Wu S, Zhang R. Zhou W, et al. Among authors: kannan t. Cancer Cell. 2023 Apr 10;41(4):740-756.e10. doi: 10.1016/j.ccell.2023.03.002. Epub 2023 Mar 23. Cancer Cell. 2023. PMID: 36963401 Free PMC article.
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer.
Mirji G, Worth A, Bhat SA, El Sayed M, Kannan T, Goldman AR, Tang HY, Liu Q, Auslander N, Dang CV, Abdel-Mohsen M, Kossenkov A, Stanger BZ, Shinde RS. Mirji G, et al. Among authors: kannan t. Sci Immunol. 2022 Sep 9;7(75):eabn0704. doi: 10.1126/sciimmunol.abn0704. Epub 2022 Sep 9. Sci Immunol. 2022. PMID: 36083892 Free PMC article.
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Indeglia A, Leung JC, Miller SA, Leu JI, Dougherty JF, Clarke NL, Kirven NA, Shao C, Ke L, Lovell S, Barnoud T, Lu DY, Lin C, Kannan T, Battaile KP, Yang THL, Batista Oliva I, Claiborne DT, Vogel P, Liu L, Liu Q, Nefedova Y, Cassel J, Auslander N, Kossenkov AV, Karanicolas J, Murphy ME. Indeglia A, et al. Among authors: kannan t. Cancer Discov. 2023 Jul 7;13(7):1696-1719. doi: 10.1158/2159-8290.CD-22-1315. Cancer Discov. 2023. PMID: 37140445 Free PMC article.
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer.
Miller KD, O'Connor S, Pniewski KA, Kannan T, Acosta R, Mirji G, Papp S, Hulse M, Mukha D, Hlavaty SI, Salcido KN, Bertolazzi F, Srikanth YVV, Zhao S, Wellen KE, Shinde RS, Claiborne DT, Kossenkov A, Salvino JM, Schug ZT. Miller KD, et al. Among authors: kannan t. Nat Cancer. 2023 Oct;4(10):1491-1507. doi: 10.1038/s43018-023-00636-6. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723305
Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging.
Singh S, Giron LB, Shaikh MW, Shankaran S, Engen PA, Bogin ZR, Bambi SA, Goldman AR, Azevedo JLLC, Orgaz L, de Pedro N, González P, Giera M, Verhoeven A, Sánchez-López E, Pandrea I, Kannan T, Tanes CE, Bittinger K, Landay AL, Corley MJ, Keshavarzian A, Abdel-Mohsen M. Singh S, et al. Among authors: kannan t. Microbiome. 2024 Feb 22;12(1):31. doi: 10.1186/s40168-024-01758-4. Microbiome. 2024. PMID: 38383483 Free PMC article.
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo.
Tursi NJ, Xu Z, Helble M, Walker S, Liaw K, Chokkalingam N, Kannan T, Wu Y, Tello-Ruiz E, Park DH, Zhu X, Wise MC, Smith TRF, Majumdar S, Kossenkov A, Kulp DW, Weiner DB. Tursi NJ, et al. Among authors: kannan t. Front Immunol. 2023 Feb 23;14:1072810. doi: 10.3389/fimmu.2023.1072810. eCollection 2023. Front Immunol. 2023. PMID: 36911698 Free PMC article.
Distinct Intestinal Microbial Signatures Linked to Accelerated Biological Aging in People with HIV.
Singh S, Giron LB, Shaikh MW, Shankaran S, Engen PA, Bogin ZR, Bambi SA, Goldman AR, Azevedo JLLC, Orgaz L, de Pedro N, González P, Giera M, Verhoeven A, Sánchez-López E, Pandrea IV, Kannan T, Tanes CE, Bittinger K, Landay AL, Corley MJ, Keshavarzian A, Abdel-Mohsen M. Singh S, et al. Among authors: kannan t. Res Sq [Preprint]. 2023 Oct 30:rs.3.rs-3492242. doi: 10.21203/rs.3.rs-3492242/v1. Res Sq. 2023. PMID: 37961645 Free PMC article. Updated. Preprint.
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.
Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, Hojecki CE, Canziani GA, Chaiken I, Kannan T, Moffat E, Embury-Hyatt C, Wooton SK, Kossenkov A, Patel A, Kobasa D, Kutzler MA, Haddad EK, Weiner DB. Gary EN, et al. Among authors: kannan t. Front Immunol. 2023 Mar 14;14:1138609. doi: 10.3389/fimmu.2023.1138609. eCollection 2023. Front Immunol. 2023. PMID: 36999023 Free PMC article.
PARP1 Inhibition Halts EBV+ Lymphoma Progression by Disrupting the EBNA2/MYC Axis.
Napoletani G, Soldan SS, Kannan T, Preston-Alp S, Vogel P, Maestri D, Caruso LB, Kossenkov A, Sobotka A, Lieberman PM, Tempera I. Napoletani G, et al. Among authors: kannan t. bioRxiv [Preprint]. 2023 Jul 7:2023.07.05.547847. doi: 10.1101/2023.07.05.547847. bioRxiv. 2023. PMID: 37461649 Free PMC article. Preprint.
15 results